2 Revision history for Bioperl core modules
6 o Bio::Tools::Run has been broken off into a new pkg bioperl-run,
7 this separation removes some of the complexity in our test suite
8 and separates the core modules in bioperl from those that need
9 external programs to run.
11 o With latest ExtUtils::MakeMaker module installed SGI/IRIX should
12 not run into trouble running the makefile
14 o Bio::Location and Bio::SeqIO::FTHelper are fixed to properly
15 read,create,and write locations for grouped/split locations
16 (like mRNA features on genomic sequence).
18 o Bio::Tools::Phlyo added for wrappers for parsing Molphy (protml)
19 and PAML (codeml,aaml, etc) parsing.
21 o Bio::Tree:: objects expanded to handle testing monophyly,
22 paraphyly, least common ancestor, etc.
24 o Bio::Coordinate for mapping locations from different coordinate spaces
26 o Bio::SearchIO::waba added for parsing WABA, Bio::SearchIO::hmmer
27 added for parsing hmmpfam and hmmsearch output.
29 o Bio::SearchIO::Writer::TextResultWriter for outputting
30 a pseudo-blast textfile format
35 o Note: The modules Bio::DB::GenBank and Bio::DB::GenPept provided
36 in this release will not work after December 2002 when NCBI
37 shuts off the old Entrez cgi scripts. We have already fixed
38 on our main development branch and the functionality will be
39 available in the next stable bioperl release (1.2) slated for
42 o Numerous parsing bugs in Bio::SearchIO::fasta found through
43 testset by Robin Emig. These were fixed as was the get_aln
44 method in Bio::Search::HSP::GenericHSP to handle the extra
45 context sequence that is provided with a FastA alignment.
47 o Migrating differences between Bio::Search::XX::BlastXX to
48 Bio::Search::XX::GenericXX objects. This included mechanism
49 to retrieve whole list of HSPs from Hits and whole list of Hits from
50 Results in addition to the current next_XX iterator methods that
51 are available. Added seq_inds() method to GenericHSP which identifies
52 indexes in the query or hit sequences where conserved,identical,gaps,
53 or mismatch residues are located (adapted from Steve Chervitz's
54 implementation in BlastHSP).
56 o Bio::DB::GFF bugs fixed and are necessary for latest GBrowse release.
57 Bio::DB::GFF::RelSegment is now Bio::SeqI compliant.
59 o Bio::Graphics glyph set improved and extended for GBrowse release
61 o Bio::Tree::Tree get_nodes implementation improvement thanks
62 to Howard Ross notice performance problem when writing out
65 o Bio::Location::Fuzzy::new named parameter -loc_type became
66 -location_type, Bio::Location::Simple::new named parameter
67 -seqid becamse -seq_id.
69 o Fixed major Bio::AlignIO::emboss parsing bug on needle output,
70 was mis-detecting that gaps should be placed at the beginning of
71 the alignment when the best alignment starts internally in the
76 o Minor bug fixes to Bio::DB:GFF. Glyph sets improved.
78 o Parser fixes in SearchIO blast, fasta for more complete WU BLAST
79 and mixed (3.3 - 3.4) versions of FASTA.
81 o Small API change to add methods for completeness across
82 implementations of Bio::Search objects. These new methods
83 in the interface are implemented by the GenericXX object as well
84 as the BlastXX objects.
85 * Bio::Search::Result::ResultI
86 - hits() method returns list of all Hits (next_hit is an
89 * Bio::Search::Hit::HitI
90 - hsps() method returns list of all HSPs (next_hsp is an
93 o The Bio::SearchIO::Writer classes have been fixed to handle results
94 created from either psiblast (Search::BlastXX objects) or
95 blast|fasta|blastxml objects (Search::GenericXX objects). More work
96 has to be done here to make it work properly and will nee major
99 o Bugs in Bio::Tools::HMMER fixed, including
100 * #1178 - Root::IO destructor wasn't being called
101 * #1034 - filter_on_cutoff now behaves properly
103 o Bio::SeqFeature::Computation initialization args fixed and
106 o Tests are somewhat cleaner, flat.t now properly cleans up after itsself,
108 o Updated FAQ with more example based answers to typical questions
110 o Bug #1202 was fixed which would improperly join together qual values
111 parsed by Bio::SeqIO::qual when a trailing space was not present before
114 1.0.0 Major Stable Release
116 This represents a major release of bioperl with significant
117 improvements over the 0.7.x series of releases.
119 o Bio::Tools::Blast is officially deprecated. Please see
120 Bio::SearchIO for BLAST and FastA parsing.
122 o The methods trunc() and subseq() in Bio::PrimarySeqI now accepts
123 Bio::LocationI objects as well as start/end.
125 o Bio::Biblio contains modules for Bibliographic data.
126 Bio::DB::Biblio contains the query modules. Additionally one can
127 parse medlinexml from the ebi bibliographic query service (BQS)
128 system and Pubmed xml from NCBI. See Martin Senger's
129 documentation in Bio::Biblio for more information.
131 o Bio::DB::Registry is a sequence database registry part of
132 Open Bioinformatics Database Access. See
133 http://obda.open-bio.org for more information.
135 o File-based and In-Memory Sequence caching is provided by
136 Bio::DB::InMemoryCache and Bio::DB::FileCache which acts like a
139 o Bio::Graphics for rendering sequences as PNG,JPG, or GIFs has
140 been added by Lincoln Stein.
142 o XEMBL SOAP service access in provided in Bio::DB::XEMBL.
144 o A FAQ has been started and is included in the release to provide
145 a starting point for frequent questions and issues.
147 0.9.3 Developer's release
149 o Event based parsing system improved (SearchIO). With parsers for
150 XML Blast (blastxml), Text Blast (blast), and FASTA results (fasta).
151 Additionally a lazy parsing system for text and html blast reports was
152 added and is called psiblast (name subject to change in future releases).
154 o Bio::Search objects improved and standardized with associated Interfaces
155 written. The concept of a search "Hit" was standardized to be called
156 "hit" consistently and the use of "subject" was deprecated in all active
159 o Bio::Structure added (since 0.9.1) for Protein structure objects
160 and PDB parser to retrieve and write these structures from data files.
162 o Several important Bio::DB::GFF bug fixes for handling features that
163 are mapped to multiple reference points. Updated mysql adaptor
164 so as to be able to store large (>100 megabase) chunks of DNA into
165 Bio::DB::GFF databases.
167 0.9.2 Developer's release
169 o Bio::Search and Bio::SearchIO system introduced for event based
170 parsing of Blast,Fasta reports Bio::SearchIO supports ncbi BLAST
171 in text and XML and FASTA reports in standard output format.
173 o Bio::Tree and Bio::TreeIO for phylogenetic trees. A Random tree
174 generator is included in Bio::TreeIO::RandomTrees and a
175 statistics module for evaluating.
177 o Bio::DB::GFF, Lincoln Stein's GFF database suitable as a DB
178 server for DAS servers.
180 o Bio::Tools::BPlite is provides more robust parsing of BLAST
181 files. The entire BPlite system migrated to using Bio::Root::IO
184 o Bio::Tools::Alignment for Consed and sequence Trimming
187 o Bio::Structure for Protein structure information and parsing
189 o Bio::DB::GenBank/Bio::DB::GenPept updated to new NCBI Entrez
190 cgi-bin entry point which should be more reliable.
192 o Bio::Map and Bio::MapIO for biological map navigation and a
193 framework afor parsing them in. Only preliminary work here.
195 o Interface for executing EMBOSS programs locally in Bio::Factory::EMBOSS
196 Future work will integrate Pise and allow submission of analysis on
199 o Bio::AnnotationCollectionI and Bio::Annotation::Collection
200 introduced as new objects for handling Sequence Annotation
201 information (dblinks, references, etc) and is more robust that
204 o Bio::Tools::FASTAParser introduced.
206 o Scripts from the bioperl script submission project and new
207 scripts from bioperl authors are included in "scripts" directory.
209 o Factory objects and interfaces are being introduced and are more
212 o Bio::Root::Root introduced as the base object while
213 Bio::Root::RootI is now simply an interface.
215 o Bio::DB::RefSeq provides database access to copy of the NCBI
216 RefSeq database using the EBI dbfetch script.
218 0.9.0 Developer's release
220 o perl version at least 5.005 is now required instead of perl 5.004
222 o Bio::Tools::Run::RemoteBlast is available for running remote
225 o Bio::Tools::BPbl2seq was fixed to handle multiple HSPs.
227 o Bio::SeqFeature::GeneStructure migrated to Bio::SeqFeature::Gene.
228 Also added are related modules UTR3, UTR5, Exon, Intron,
229 Promotor, PolyA and Transcript.
231 o Speedup of translate method in PrimarySeq
233 o Bio::SimpleAlign has new methods: location_from_column(), slice(),
234 select(), dot(), get_seq_by_pos(), column_from_residue_number()
236 o Various fixes to Variation toolkit
238 o Bio::DB::EMBL provides database access to EMBL sequence data.
239 Bio::DB::Universal provides a central way to point to indexes
240 and dbs in a single interface.
242 o Bio::DB::GFF - a database suitable for running DAS servers locally.
244 o Bio::Factory::EMBOSS is still in design phase as is
245 Bio::Factory::ApplicationFactoryI
247 o Dia models for bioperl design are provided in the models/ directory
249 0.7.2 Bug fix release
251 o documentation fixes in many modules - SYNOPSIS code verified
252 to be runnable in many (but not all modules)
254 o corrected MANIFEST file from 0.7.1 release
256 o Bug fix in Bio::SeqIO::FTHelper to properly handle
259 o Bio::SeqIO::genbank
260 * Correct parsing and writing of genbank format with protein data
261 * moltype and molecule separation
263 o Bio::SeqIO::largefasta fix to avoid inifinite loops
265 o Bio::SimpleAlign fixed to correctly handle consensus
268 o Bio::Tools::HMMER supports hmmer 2.2g
270 o Bio::Tools::BPlite to support report type specific parsing. Most
271 major changes are not on the 0.7 branch.
273 o Bio::Tools::Run::StandAloneBlast exists_blast() fixed and works
276 o Bio::Variation::AAChange/RNAChange corrected labels and mutated alleles
277 in several types of mutations:
278 1.) AA level: deletion, complex
279 2.) AA level: complex, inframe
280 3.) RNA level: silent
282 o BPbl2seq parsing of empty reports will not die, but will return
283 a valid, empty, Bio::SeqFeature::SimilarityFeature for
284 $report->query() and $report->subject() methods. So an easy
285 way to test if report was empty is to see if
286 $report->query->seqname is undefined.
288 0.7.1 Bug fix release
290 o Better parsing of genbank/EMBL files especially fixing bugs
291 related to Feature table parsing and locations on remote
292 sequences. Additionally, species name parsing was better.
294 o Bio::SeqIO::genbank can parse now NCBI produced genbank database
295 which include a number of header lines.
297 o More strict genbank and EMBL format writing (corrected number of
298 spaces where appropriate).
300 o Bio::Tools::BPlite can better parse BLASTX reports - see BUGS
301 for related BPlite BUGS that are unresolved in this release.
303 o Bio::DB::GenBank, Bio::DB::GenPept have less problems
304 downloading sequences from NCBI via HTTP. Bio::DB::SwissProt can
305 use expasy mirrors or EBI dbfetch cgi-script.
307 o A moderate number of documentation improvements were made as
308 well to provide a better code synopsis in each module.
311 0.7 Large number of changes, including refactoring of the
312 Object system, new parsers, new functionality and
313 all round better system. Highlights are:
316 o Refactored root of inheritance: moved to a lightweight Bio::Root::RootI;
317 Bio::Root::IO for I/O and file/handle capabilities.
319 o Imported BPlite modules from Ian Korf for BLAST
320 parsing. This is considered the supported BLAST parser;
321 Bio::Tools::Blast.pm will eventually phase out due to lack of support.
323 o Improved Sequence Feature model. Added complete location
324 modelling (with fuzzy and compound locations). See
325 Bio::LocationI and the modules under Bio/Location. Added
326 support in Genbank/EMBL format parsing to completely parse
327 feature tables for complex locations.
329 o Moved special support for databanks etc to specialized modules under
330 Bio/Seq/. One of these supports very large sequences through
331 a temporary file as a backend.
333 o Explicit Gene, Transcript and Exon SeqFeature objects, supporting
334 CDS retrieval and exon shuffling.
336 o More parsers: Sim4, Genscan, MZEF, ESTScan, BPbl2seq, GFF
338 o Refactored Bio/DB/GenBank+GenPept. There is now also DB/SwissProt and
339 DB/GDB (the latter has platform-specific limitations).
341 o New analysis parser framework for HT sequence annotation (see
342 Bio::SeqAnalysisParserI and Bio::Factory::SeqAnalysisParserFactory)
344 o New Alignment IO framework
346 o New Index modules (Swissprot)
348 o New modules for running Blast within perl
349 (Bio::Tools::Run::StandAloneBlast). Added modules for running
350 Multiple Sequence Alignment tools ClustalW and TCoffee
351 (Bio::Tools::Run::Alignment).
353 o New Cookbook-style tutorial (see bptutorial.pl). Improved
354 documentation across the package.
356 o Much improved cross platform support. Many known incompatibilities
357 have been fixed; however, NT and Mac do not work across the entire
358 setup (see PLATFORMS).
360 o Many bug fixes, code restructuring, etc. Overall stability and
361 maintainability benefit a lot.
363 o A total of 957 automatic tests
368 There are very few functionality changes but a large
369 number of software improvements/bug fixes across the package.
371 o The EMBL/GenBank parsing are improved.
373 o The Swissprot reading is improved. Swissprot writing
374 is disabled as it doesn't work at all. This needs to
377 o BLAST reports with no hits are correctly parsed.
379 o Several other bugs of the BLAST parser (regular expressions, ...)
382 o Old syntax calls have been replaced with more modern syntax
384 o Modules that did not work at all, in particular the Sim4
385 set have been removed
387 o Bio::SeqFeature::Generic and Bio::SeqFeature::FeaturePair
388 have improved compliance with interface specs and documentation
390 o Mailing list documentation updated throughout the distribution
392 o Most minor bug fixes have happened.
394 o The scripts in /examples now work and have the modern syntax
395 rather than the deprecated syntax
398 0.6.1 Sun April 2 2000
400 o Sequences can have Sequence Features attached to them
401 - The sequence features can be read from or written to
402 EMBL and GenBank style flat files
404 o Objects for Annotation, including References (but not
405 full medline abstracts), Database links and Comments are
408 o A Species object to represent nodes on a taxonomy tree
411 o The ability to parse HMMER and Sim4 output has been added
413 o The Blast parsing has been improved, with better PSI-BLAST
414 support and better overall behaviour.
416 o Flat file indexed databases provide both random access
417 and sequential access to their component sequences.
419 o A CodonTable object has been written with all known
420 CodonTables accessible.
422 o A number of new lightweight analysis tools have been
423 added, such as molecular weight determination.
425 The 0.6 release also has improved software engineering
427 o The sequence objects have been rewritten, providing more
428 maintainable and easier to implement objects. These
429 objects are backwardly compatible with the 0.05.1 objects
431 o Many objects are defined in terms of interfaces and then
432 a Perl implementation has been provided. The interfaces
433 are found in the 'I' files (module names ending in 'I').
435 This means that it is possible to wrap C/CORBA/SQL access
436 as true "bioperl" objects, compatible with the rest of
439 o The SeqIO system has been overhauled to provide better
440 processing and perl-like automatic interpretation of <>
443 o Many more tests have been added (a total of 172 automatic
444 tests are now run before release).
448 0.05.1 Tue Jun 29 05:30:44 1999
449 - Central distribution now requires Perl 5.004. This was
450 done to get around 5.003-based problems in Bio/Index/*
452 - Various bug fixes in the Bio::Tools::Blast modules
453 including better exception handling and PSI-Blast
454 support. See Bio/Tools/Blast/CHANGES for more.
455 - Fixed the Parse mechanism in Seq.pm to use readseq.
456 Follow the instructions in README for how to install
457 it (basically, you have to edit Parse.pm).
458 - Improved documentation of Seq.pm, indicating where
459 objects are returned and where strings are returned.
460 - Fixed uninitialized warnings in Bio::Root::Object.pm
461 and Bio::Tools::SeqPattern.pm.
462 - Bug fixes for PR#s: 30,31,33-35,41,42,44,45,47-50,52.
464 0.05 Sun Apr 25 01:14:11 1999
465 - Bio::Tools::Blast modules have less memory problems
466 and faster parsing. Webblast uses LWP and supports
467 more functionality. See Bio/Tools/Blast/CHANGES for more.
468 - The Bio::SeqIO system has been started, moving the
469 sequence reformatting code out of the sequence object
470 - The Bio::Index:: system has been started, providing
471 generic index capabilities and specifically works for
472 Fasta formatted databases and EMBL .dat formatted
474 - The Bio::DB:: system started, providing access to
475 databases, both via flat file + index (see above) and
477 - The scripts/ directory, where industrial strength scripts
478 are put has been started.
479 - Many changes - a better distribution all round.
481 0.04.4 Wed Feb 17 02:20:13 1999
482 - Bug fixes in the Bio::Tools::Blast modules and postclient.pl
483 (see Bio::Tools::Blast::CHANGES).
484 - Fixed a bug in Bio::Tools::Fasta::num_seqs().
485 - Beefed up the t/Fasta.t test script.
486 - Small fix in Bio::Seq::type() (now always returns a string).
487 - Changed Bio::Root::Utilities::get_newline_char() to
488 get_newline() since it could return more than one char.
489 - Added $NEWLINE and $TIMEOUT_SECS to Bio::Root::Global.
490 - Changed default timeout to 20 seconds (was 3).
491 - Moved lengthy modification notes to the bottom of some files.
492 - Fixed SimpleAlign write_fasta bug.
493 - Beefed up SimpleAlign.t test
495 0.04.3 Thu Feb 4 07:48:53 1999
496 - Bio::Root::Object.pm and Global.pm now detect when
497 script is run as a CGI and suppress output that is only
498 appropriate when running interactively.
499 - Bio::Root::Err::_set_context() adds name of script ($0).
500 - Added comments in Bio::Tools::WWW.pm and Bio::Root::Utilities.pm
501 regarding the use of the static objects via the qw(:obj) tag.
502 - Fixed the ambiguous reverse calls in Seq.pm and UnivAln.pm to
503 CORE::reverse, avoiding Perl warnings.
504 - Bug fixes in Bio::Tools::Blast modules (version 0.074) and
505 example scripts (see Bio::Tools::Blast::CHANGES).
506 - examples/seq/seqtools.pl no longer always warns about using
507 -prot or -nucl command-line arguments; only when using the
509 - Methods added to Bio::Root::Utilities: create_filehandle(),
510 get_newline_char(), and taste_file() to generalize filehandle
511 creation and autodetect newline characters in files/streams
512 (see bug report #19).
513 - Bio::Root::IOManager::read() now handles timeouts and uses
514 Utilities::create_filehandle().
515 - Bio::Tools::Fasta.pm uses Utilities::get_newline_char() instead
516 of hardwiring in "\n".
517 - Bug fixes in the Bio::SimpleAlign and Bio::Tools::pSW
519 0.04.2 Wed Dec 30 02:27:36 1998
520 - Bug fixes in Bio::Tools::Blast modules, version 0.073
521 (see Bio::Tools::Blast::CHANGES).
522 - Changed reverse calls in Bio/Seq.pm and Bio/UnivAln.pm
523 to CORE::reverse (prevents ambiguous warnings with 5.005).
524 - Appending '.tmp.bioperl' to temporary files created by
525 Bio::Root::Utilities::compress() or uncompress() to
526 make it easy to identify & cleanup these files as needed.
527 - Developers: Created CVS branch release-0-04-bug from
528 release-0-04-1. Before making bug fixes to the 0.04.1 release,
529 be sure to cvs checkout this branch into a clean area.
531 0.04.1 Wed Dec 16 05:39:15 1998
532 - Bug fixes in Bio::Tools::Blast modules, version 0.072
533 (see Bio::Tools::Blast::CHANGES).
534 - Compile/SW/Makefile.PL now removes *.o and *.a files
537 0.04 Tue Dec 8 07:49:19 1998
538 - Lots of new modules added including:
539 * Ewan Birney's Bio::SimpleAlign.pm, Bio::Tools::AlignFactory.pm,
540 and Bio/Compile directory containing XS-linked C code for
541 creating Smith-Waterman sequence alignments from within Perl.
542 * Steve Chervitz's Blast distribution has been incorporated.
543 * Georg Fuellen's Bio::UnivAln.pm for multiple alignment objects.
544 - Bio/examples directory for demo scripts for all included modules.
545 - Bio/t directory containing test suit for all included modules.
546 - For changes specific to the Blast-related modules prior to
547 incorporation in this central distribution, see the CHANGES
548 file in the Bio/Tools/Blast directory.
550 0.01 Tue Sep 8 14:23:22 1998
551 - original version from central CVS tree; created by h2xs 1.18