3 subsetdef: goslim_candida "Candida GO slim"
4 subsetdef: goslim_generic "Generic GO slim"
5 subsetdef: goslim_goa "GOA and proteome slim"
6 subsetdef: goslim_pir "PIR GO slim"
7 subsetdef: goslim_plant "Plant GO slim"
8 subsetdef: goslim_yeast "Yeast GO slim"
9 subsetdef: gosubset_prok "Prokaryotic GO subset"
10 default-namespace: gene_ontology
14 name: molecular_function
15 namespace: molecular_function
16 def: "Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions." [GOC:go_curators]
17 comment: Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. Note that when this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code ND, no data, is used to indicate this.
18 subset: goslim_candida
19 subset: goslim_generic
25 synonym: "molecular function unknown" NARROW []
29 name: catalytic activity
30 namespace: molecular_function
31 def: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [ISBN:0198506732]
32 subset: goslim_generic
37 synonym: "enzyme activity" RELATED []
38 is_a: GO:0003674 ! molecular_function
42 name: biological_process
43 namespace: biological_process
44 def: "Those processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end." [GOC:go_curators, GOC:isa_complete]
45 comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. Note that when this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code ND, no data, is used to indicate this.
46 subset: goslim_candida
47 subset: goslim_generic
53 synonym: "biological process unknown" NARROW []
54 synonym: "physiological process" EXACT []
58 name: transferase activity
59 namespace: molecular_function
60 def: "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [ISBN:0198506732]
61 subset: goslim_candida
62 subset: goslim_generic
69 is_a: GO:0003824 ! catalytic activity
73 name: positive regulation of catalytic activity
74 namespace: biological_process
75 def: "Any process that activates or increases the activity of an enzyme." [GOC:jl, GOC:tb]
77 synonym: "activation of enzyme activity" NARROW []
78 synonym: "positive regulation of enzyme activity" EXACT []
79 synonym: "stimulation of enzyme activity" NARROW []
80 synonym: "up regulation of enzyme activity" EXACT []
81 synonym: "up-regulation of enzyme activity" EXACT []
82 synonym: "upregulation of enzyme activity" EXACT []
83 is_a: GO:0050790 ! regulation of catalytic activity
84 intersection_of: GO:0065007 ! biological regulation
85 intersection_of: positively_regulates GO:0003824 ! catalytic activity
86 relationship: positively_regulates GO:0003824 ! catalytic activity
90 name: regulation of catalytic activity
91 namespace: biological_process
92 def: "Any process that modulates the activity of an enzyme." [GOC:ai]
94 synonym: "regulation of enzyme activity" EXACT []
95 is_a: GO:0065009 ! regulation of a molecular function
96 intersection_of: GO:0065007 ! biological regulation
97 intersection_of: regulates GO:0003824 ! catalytic activity
98 relationship: regulates GO:0003824 ! catalytic activity
102 name: regulation of transferase activity
103 namespace: biological_process
104 def: "Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [EC:2.-.-.-, GOC:ai]
105 subset: gosubset_prok
106 synonym: "transferase regulator" EXACT []
107 is_a: GO:0050790 ! regulation of catalytic activity
108 intersection_of: GO:0065007 ! biological regulation
109 intersection_of: regulates GO:0016740 ! transferase activity
110 relationship: regulates GO:0016740 ! transferase activity
114 name: positive regulation of transferase activity
115 namespace: biological_process
116 def: "Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." [GOC:ai]
117 subset: gosubset_prok
118 synonym: "activation of transferase activity" NARROW []
119 synonym: "stimulation of transferase activity" NARROW []
120 synonym: "transferase activator" EXACT []
121 synonym: "up regulation of transferase activity" EXACT []
122 synonym: "up-regulation of transferase activity" EXACT []
123 synonym: "upregulation of transferase activity" EXACT []
124 is_a: GO:0043085 ! positive regulation of catalytic activity
125 is_a: GO:0051338 ! regulation of transferase activity
126 intersection_of: GO:0065007 ! biological regulation
127 intersection_of: positively_regulates GO:0016740 ! transferase activity
128 relationship: positively_regulates GO:0016740 ! transferase activity
132 name: biological regulation
133 namespace: biological_process
134 def: "Any process that modulates the frequency, rate or extent of any biological process, quality or function." [GOC:isa_complete]
136 subset: gosubset_prok
137 synonym: "regulation" BROAD []
138 is_a: GO:0008150 ! biological_process
142 name: regulation of a molecular function
143 namespace: biological_process
144 def: "Any process that modulates the frequency, rate or extent of molecular functions. Molecular functions are elemental biological activities occurring at the molecular level, such as catalysis or binding." [GOC:isa_complete]
145 subset: gosubset_prok
146 is_a: GO:0065007 ! biological regulation
149 id: positively_regulates
150 name: positively_regulates
151 namespace: gene_ontology
152 is_a: regulates ! regulates
157 namespace: gene_ontology