2 Revision history for Bioperl core modules
4 1.1.1 Developer release
6 o Deprecated modules are now listed in the DEPRECATED file
8 o New HowTo documents located in doc/howto describing
11 o Note that bugs are now stored at bugzilla.bioperl.org
12 and all old bugs are searchable through the bugzilla interface.
14 o Several reported bugs in Bio::Tools::Sigcleave and Bio::SimpleAlign
17 o Support for Genewise parsing in Bio::Tools::Genewise
19 o Speedup to the Bio::Root::Root object method _rearrange.
20 A global _load_module method was implemented to simplify the
21 dynamic loading of modules ala Bio::SeqIO::genbank. This
22 method is now used by all the XXIO (AlignIO,TreeIO,SearchIO,SeqIO,
25 o Several performance improvements to sequence parsing in Bio::SeqIO.
26 Attempt to speedup by reducing object creation overhead.
28 o Bio::DB::GenBank and Bio::DB::GenPept use the NCBI's approved
29 method for sequence retrieval with their E-utils CGI scripts.
30 More work to support Entrez queries to their fullest is planned
35 o Bio::Tools::Run has been broken off into a new pkg bioperl-run,
36 this separation removes some of the complexity in our test suite
37 and separates the core modules in bioperl from those that need
38 external programs to run.
40 o With latest ExtUtils::MakeMaker module installed SGI/IRIX should
41 not run into trouble running the makefile
43 o Bio::Location and Bio::SeqIO::FTHelper are fixed to properly
44 read,create,and write locations for grouped/split locations
45 (like mRNA features on genomic sequence).
47 o Bio::Tools::Phlyo added for wrappers for parsing Molphy (protml)
48 and PAML (codeml,aaml, etc) parsing.
50 o Bio::Tree:: objects expanded to handle testing monophyly,
51 paraphyly, least common ancestor, etc.
53 o Bio::Coordinate for mapping locations from different coordinate spaces
55 o Bio::SearchIO::waba added for parsing WABA, Bio::SearchIO::hmmer
56 added for parsing hmmpfam and hmmsearch output.
58 o Bio::SearchIO::Writer::TextResultWriter for outputting
59 a pseudo-blast textfile format
64 o Note: The modules Bio::DB::GenBank and Bio::DB::GenPept provided
65 in this release will not work after December 2002 when NCBI
66 shuts off the old Entrez cgi scripts. We have already fixed
67 on our main development branch and the functionality will be
68 available in the next stable bioperl release (1.2) slated for
71 o Numerous parsing bugs in Bio::SearchIO::fasta found through
72 testset by Robin Emig. These were fixed as was the get_aln
73 method in Bio::Search::HSP::GenericHSP to handle the extra
74 context sequence that is provided with a FastA alignment.
76 o Migrating differences between Bio::Search::XX::BlastXX to
77 Bio::Search::XX::GenericXX objects. This included mechanism
78 to retrieve whole list of HSPs from Hits and whole list of Hits from
79 Results in addition to the current next_XX iterator methods that
80 are available. Added seq_inds() method to GenericHSP which identifies
81 indexes in the query or hit sequences where conserved,identical,gaps,
82 or mismatch residues are located (adapted from Steve Chervitz's
83 implementation in BlastHSP).
85 o Bio::DB::GFF bugs fixed and are necessary for latest GBrowse release.
86 Bio::DB::GFF::RelSegment is now Bio::SeqI compliant.
88 o Bio::Graphics glyph set improved and extended for GBrowse release
90 o Bio::Tree::Tree get_nodes implementation improvement thanks
91 to Howard Ross notice performance problem when writing out
94 o Bio::Location::Fuzzy::new named parameter -loc_type became
95 -location_type, Bio::Location::Simple::new named parameter
96 -seqid becamse -seq_id.
98 o Fixed major Bio::AlignIO::emboss parsing bug on needle output,
99 was mis-detecting that gaps should be placed at the beginning of
100 the alignment when the best alignment starts internally in the
103 1.0.1 Bug fix release
105 o Minor bug fixes to Bio::DB:GFF. Glyph sets improved.
107 o Parser fixes in SearchIO blast, fasta for more complete WU BLAST
108 and mixed (3.3 - 3.4) versions of FASTA.
110 o Small API change to add methods for completeness across
111 implementations of Bio::Search objects. These new methods
112 in the interface are implemented by the GenericXX object as well
113 as the BlastXX objects.
114 * Bio::Search::Result::ResultI
115 - hits() method returns list of all Hits (next_hit is an
118 * Bio::Search::Hit::HitI
119 - hsps() method returns list of all HSPs (next_hsp is an
122 o The Bio::SearchIO::Writer classes have been fixed to handle results
123 created from either psiblast (Search::BlastXX objects) or
124 blast|fasta|blastxml objects (Search::GenericXX objects). More work
125 has to be done here to make it work properly and will nee major
128 o Bugs in Bio::Tools::HMMER fixed, including
129 * #1178 - Root::IO destructor wasn't being called
130 * #1034 - filter_on_cutoff now behaves properly
132 o Bio::SeqFeature::Computation initialization args fixed and
135 o Tests are somewhat cleaner, flat.t now properly cleans up after itsself,
137 o Updated FAQ with more example based answers to typical questions
139 o Bug #1202 was fixed which would improperly join together qual values
140 parsed by Bio::SeqIO::qual when a trailing space was not present before
143 1.0.0 Major Stable Release
145 This represents a major release of bioperl with significant
146 improvements over the 0.7.x series of releases.
148 o Bio::Tools::Blast is officially deprecated. Please see
149 Bio::SearchIO for BLAST and FastA parsing.
151 o The methods trunc() and subseq() in Bio::PrimarySeqI now accepts
152 Bio::LocationI objects as well as start/end.
154 o Bio::Biblio contains modules for Bibliographic data.
155 Bio::DB::Biblio contains the query modules. Additionally one can
156 parse medlinexml from the ebi bibliographic query service (BQS)
157 system and Pubmed xml from NCBI. See Martin Senger's
158 documentation in Bio::Biblio for more information.
160 o Bio::DB::Registry is a sequence database registry part of
161 Open Bioinformatics Database Access. See
162 http://obda.open-bio.org for more information.
164 o File-based and In-Memory Sequence caching is provided by
165 Bio::DB::InMemoryCache and Bio::DB::FileCache which acts like a
168 o Bio::Graphics for rendering sequences as PNG,JPG, or GIFs has
169 been added by Lincoln Stein.
171 o XEMBL SOAP service access in provided in Bio::DB::XEMBL.
173 o A FAQ has been started and is included in the release to provide
174 a starting point for frequent questions and issues.
176 0.9.3 Developer's release
178 o Event based parsing system improved (SearchIO). With parsers for
179 XML Blast (blastxml), Text Blast (blast), and FASTA results (fasta).
180 Additionally a lazy parsing system for text and html blast reports was
181 added and is called psiblast (name subject to change in future releases).
183 o Bio::Search objects improved and standardized with associated Interfaces
184 written. The concept of a search "Hit" was standardized to be called
185 "hit" consistently and the use of "subject" was deprecated in all active
188 o Bio::Structure added (since 0.9.1) for Protein structure objects
189 and PDB parser to retrieve and write these structures from data files.
191 o Several important Bio::DB::GFF bug fixes for handling features that
192 are mapped to multiple reference points. Updated mysql adaptor
193 so as to be able to store large (>100 megabase) chunks of DNA into
194 Bio::DB::GFF databases.
196 0.9.2 Developer's release
198 o Bio::Search and Bio::SearchIO system introduced for event based
199 parsing of Blast,Fasta reports Bio::SearchIO supports ncbi BLAST
200 in text and XML and FASTA reports in standard output format.
202 o Bio::Tree and Bio::TreeIO for phylogenetic trees. A Random tree
203 generator is included in Bio::TreeIO::RandomTrees and a
204 statistics module for evaluating.
206 o Bio::DB::GFF, Lincoln Stein's GFF database suitable as a DB
207 server for DAS servers.
209 o Bio::Tools::BPlite is provides more robust parsing of BLAST
210 files. The entire BPlite system migrated to using Bio::Root::IO
213 o Bio::Tools::Alignment for Consed and sequence Trimming
216 o Bio::Structure for Protein structure information and parsing
218 o Bio::DB::GenBank/Bio::DB::GenPept updated to new NCBI Entrez
219 cgi-bin entry point which should be more reliable.
221 o Bio::Map and Bio::MapIO for biological map navigation and a
222 framework afor parsing them in. Only preliminary work here.
224 o Interface for executing EMBOSS programs locally in Bio::Factory::EMBOSS
225 Future work will integrate Pise and allow submission of analysis on
228 o Bio::AnnotationCollectionI and Bio::Annotation::Collection
229 introduced as new objects for handling Sequence Annotation
230 information (dblinks, references, etc) and is more robust that
233 o Bio::Tools::FASTAParser introduced.
235 o Scripts from the bioperl script submission project and new
236 scripts from bioperl authors are included in "scripts" directory.
238 o Factory objects and interfaces are being introduced and are more
241 o Bio::Root::Root introduced as the base object while
242 Bio::Root::RootI is now simply an interface.
244 o Bio::DB::RefSeq provides database access to copy of the NCBI
245 RefSeq database using the EBI dbfetch script.
247 0.9.0 Developer's release
249 o perl version at least 5.005 is now required instead of perl 5.004
251 o Bio::Tools::Run::RemoteBlast is available for running remote
254 o Bio::Tools::BPbl2seq was fixed to handle multiple HSPs.
256 o Bio::SeqFeature::GeneStructure migrated to Bio::SeqFeature::Gene.
257 Also added are related modules UTR3, UTR5, Exon, Intron,
258 Promotor, PolyA and Transcript.
260 o Speedup of translate method in PrimarySeq
262 o Bio::SimpleAlign has new methods: location_from_column(), slice(),
263 select(), dot(), get_seq_by_pos(), column_from_residue_number()
265 o Various fixes to Variation toolkit
267 o Bio::DB::EMBL provides database access to EMBL sequence data.
268 Bio::DB::Universal provides a central way to point to indexes
269 and dbs in a single interface.
271 o Bio::DB::GFF - a database suitable for running DAS servers locally.
273 o Bio::Factory::EMBOSS is still in design phase as is
274 Bio::Factory::ApplicationFactoryI
276 o Dia models for bioperl design are provided in the models/ directory
278 0.7.2 Bug fix release
280 o documentation fixes in many modules - SYNOPSIS code verified
281 to be runnable in many (but not all modules)
283 o corrected MANIFEST file from 0.7.1 release
285 o Bug fix in Bio::SeqIO::FTHelper to properly handle
288 o Bio::SeqIO::genbank
289 * Correct parsing and writing of genbank format with protein data
290 * moltype and molecule separation
292 o Bio::SeqIO::largefasta fix to avoid inifinite loops
294 o Bio::SimpleAlign fixed to correctly handle consensus
297 o Bio::Tools::HMMER supports hmmer 2.2g
299 o Bio::Tools::BPlite to support report type specific parsing. Most
300 major changes are not on the 0.7 branch.
302 o Bio::Tools::Run::StandAloneBlast exists_blast() fixed and works
305 o Bio::Variation::AAChange/RNAChange corrected labels and mutated alleles
306 in several types of mutations:
307 1.) AA level: deletion, complex
308 2.) AA level: complex, inframe
309 3.) RNA level: silent
311 o BPbl2seq parsing of empty reports will not die, but will return
312 a valid, empty, Bio::SeqFeature::SimilarityFeature for
313 $report->query() and $report->subject() methods. So an easy
314 way to test if report was empty is to see if
315 $report->query->seqname is undefined.
317 0.7.1 Bug fix release
319 o Better parsing of genbank/EMBL files especially fixing bugs
320 related to Feature table parsing and locations on remote
321 sequences. Additionally, species name parsing was better.
323 o Bio::SeqIO::genbank can parse now NCBI produced genbank database
324 which include a number of header lines.
326 o More strict genbank and EMBL format writing (corrected number of
327 spaces where appropriate).
329 o Bio::Tools::BPlite can better parse BLASTX reports - see BUGS
330 for related BPlite BUGS that are unresolved in this release.
332 o Bio::DB::GenBank, Bio::DB::GenPept have less problems
333 downloading sequences from NCBI via HTTP. Bio::DB::SwissProt can
334 use expasy mirrors or EBI dbfetch cgi-script.
336 o A moderate number of documentation improvements were made as
337 well to provide a better code synopsis in each module.
340 0.7 Large number of changes, including refactoring of the
341 Object system, new parsers, new functionality and
342 all round better system. Highlights are:
345 o Refactored root of inheritance: moved to a lightweight Bio::Root::RootI;
346 Bio::Root::IO for I/O and file/handle capabilities.
348 o Imported BPlite modules from Ian Korf for BLAST
349 parsing. This is considered the supported BLAST parser;
350 Bio::Tools::Blast.pm will eventually phase out due to lack of support.
352 o Improved Sequence Feature model. Added complete location
353 modelling (with fuzzy and compound locations). See
354 Bio::LocationI and the modules under Bio/Location. Added
355 support in Genbank/EMBL format parsing to completely parse
356 feature tables for complex locations.
358 o Moved special support for databanks etc to specialized modules under
359 Bio/Seq/. One of these supports very large sequences through
360 a temporary file as a backend.
362 o Explicit Gene, Transcript and Exon SeqFeature objects, supporting
363 CDS retrieval and exon shuffling.
365 o More parsers: Sim4, Genscan, MZEF, ESTScan, BPbl2seq, GFF
367 o Refactored Bio/DB/GenBank+GenPept. There is now also DB/SwissProt and
368 DB/GDB (the latter has platform-specific limitations).
370 o New analysis parser framework for HT sequence annotation (see
371 Bio::SeqAnalysisParserI and Bio::Factory::SeqAnalysisParserFactory)
373 o New Alignment IO framework
375 o New Index modules (Swissprot)
377 o New modules for running Blast within perl
378 (Bio::Tools::Run::StandAloneBlast). Added modules for running
379 Multiple Sequence Alignment tools ClustalW and TCoffee
380 (Bio::Tools::Run::Alignment).
382 o New Cookbook-style tutorial (see bptutorial.pl). Improved
383 documentation across the package.
385 o Much improved cross platform support. Many known incompatibilities
386 have been fixed; however, NT and Mac do not work across the entire
387 setup (see PLATFORMS).
389 o Many bug fixes, code restructuring, etc. Overall stability and
390 maintainability benefit a lot.
392 o A total of 957 automatic tests
397 There are very few functionality changes but a large
398 number of software improvements/bug fixes across the package.
400 o The EMBL/GenBank parsing are improved.
402 o The Swissprot reading is improved. Swissprot writing
403 is disabled as it doesn't work at all. This needs to
406 o BLAST reports with no hits are correctly parsed.
408 o Several other bugs of the BLAST parser (regular expressions, ...)
411 o Old syntax calls have been replaced with more modern syntax
413 o Modules that did not work at all, in particular the Sim4
414 set have been removed
416 o Bio::SeqFeature::Generic and Bio::SeqFeature::FeaturePair
417 have improved compliance with interface specs and documentation
419 o Mailing list documentation updated throughout the distribution
421 o Most minor bug fixes have happened.
423 o The scripts in /examples now work and have the modern syntax
424 rather than the deprecated syntax
427 0.6.1 Sun April 2 2000
429 o Sequences can have Sequence Features attached to them
430 - The sequence features can be read from or written to
431 EMBL and GenBank style flat files
433 o Objects for Annotation, including References (but not
434 full medline abstracts), Database links and Comments are
437 o A Species object to represent nodes on a taxonomy tree
440 o The ability to parse HMMER and Sim4 output has been added
442 o The Blast parsing has been improved, with better PSI-BLAST
443 support and better overall behaviour.
445 o Flat file indexed databases provide both random access
446 and sequential access to their component sequences.
448 o A CodonTable object has been written with all known
449 CodonTables accessible.
451 o A number of new lightweight analysis tools have been
452 added, such as molecular weight determination.
454 The 0.6 release also has improved software engineering
456 o The sequence objects have been rewritten, providing more
457 maintainable and easier to implement objects. These
458 objects are backwardly compatible with the 0.05.1 objects
460 o Many objects are defined in terms of interfaces and then
461 a Perl implementation has been provided. The interfaces
462 are found in the 'I' files (module names ending in 'I').
464 This means that it is possible to wrap C/CORBA/SQL access
465 as true "bioperl" objects, compatible with the rest of
468 o The SeqIO system has been overhauled to provide better
469 processing and perl-like automatic interpretation of <>
472 o Many more tests have been added (a total of 172 automatic
473 tests are now run before release).
477 0.05.1 Tue Jun 29 05:30:44 1999
478 - Central distribution now requires Perl 5.004. This was
479 done to get around 5.003-based problems in Bio/Index/*
481 - Various bug fixes in the Bio::Tools::Blast modules
482 including better exception handling and PSI-Blast
483 support. See Bio/Tools/Blast/CHANGES for more.
484 - Fixed the Parse mechanism in Seq.pm to use readseq.
485 Follow the instructions in README for how to install
486 it (basically, you have to edit Parse.pm).
487 - Improved documentation of Seq.pm, indicating where
488 objects are returned and where strings are returned.
489 - Fixed uninitialized warnings in Bio::Root::Object.pm
490 and Bio::Tools::SeqPattern.pm.
491 - Bug fixes for PR#s: 30,31,33-35,41,42,44,45,47-50,52.
493 0.05 Sun Apr 25 01:14:11 1999
494 - Bio::Tools::Blast modules have less memory problems
495 and faster parsing. Webblast uses LWP and supports
496 more functionality. See Bio/Tools/Blast/CHANGES for more.
497 - The Bio::SeqIO system has been started, moving the
498 sequence reformatting code out of the sequence object
499 - The Bio::Index:: system has been started, providing
500 generic index capabilities and specifically works for
501 Fasta formatted databases and EMBL .dat formatted
503 - The Bio::DB:: system started, providing access to
504 databases, both via flat file + index (see above) and
506 - The scripts/ directory, where industrial strength scripts
507 are put has been started.
508 - Many changes - a better distribution all round.
510 0.04.4 Wed Feb 17 02:20:13 1999
511 - Bug fixes in the Bio::Tools::Blast modules and postclient.pl
512 (see Bio::Tools::Blast::CHANGES).
513 - Fixed a bug in Bio::Tools::Fasta::num_seqs().
514 - Beefed up the t/Fasta.t test script.
515 - Small fix in Bio::Seq::type() (now always returns a string).
516 - Changed Bio::Root::Utilities::get_newline_char() to
517 get_newline() since it could return more than one char.
518 - Added $NEWLINE and $TIMEOUT_SECS to Bio::Root::Global.
519 - Changed default timeout to 20 seconds (was 3).
520 - Moved lengthy modification notes to the bottom of some files.
521 - Fixed SimpleAlign write_fasta bug.
522 - Beefed up SimpleAlign.t test
524 0.04.3 Thu Feb 4 07:48:53 1999
525 - Bio::Root::Object.pm and Global.pm now detect when
526 script is run as a CGI and suppress output that is only
527 appropriate when running interactively.
528 - Bio::Root::Err::_set_context() adds name of script ($0).
529 - Added comments in Bio::Tools::WWW.pm and Bio::Root::Utilities.pm
530 regarding the use of the static objects via the qw(:obj) tag.
531 - Fixed the ambiguous reverse calls in Seq.pm and UnivAln.pm to
532 CORE::reverse, avoiding Perl warnings.
533 - Bug fixes in Bio::Tools::Blast modules (version 0.074) and
534 example scripts (see Bio::Tools::Blast::CHANGES).
535 - examples/seq/seqtools.pl no longer always warns about using
536 -prot or -nucl command-line arguments; only when using the
538 - Methods added to Bio::Root::Utilities: create_filehandle(),
539 get_newline_char(), and taste_file() to generalize filehandle
540 creation and autodetect newline characters in files/streams
541 (see bug report #19).
542 - Bio::Root::IOManager::read() now handles timeouts and uses
543 Utilities::create_filehandle().
544 - Bio::Tools::Fasta.pm uses Utilities::get_newline_char() instead
545 of hardwiring in "\n".
546 - Bug fixes in the Bio::SimpleAlign and Bio::Tools::pSW
548 0.04.2 Wed Dec 30 02:27:36 1998
549 - Bug fixes in Bio::Tools::Blast modules, version 0.073
550 (see Bio::Tools::Blast::CHANGES).
551 - Changed reverse calls in Bio/Seq.pm and Bio/UnivAln.pm
552 to CORE::reverse (prevents ambiguous warnings with 5.005).
553 - Appending '.tmp.bioperl' to temporary files created by
554 Bio::Root::Utilities::compress() or uncompress() to
555 make it easy to identify & cleanup these files as needed.
556 - Developers: Created CVS branch release-0-04-bug from
557 release-0-04-1. Before making bug fixes to the 0.04.1 release,
558 be sure to cvs checkout this branch into a clean area.
560 0.04.1 Wed Dec 16 05:39:15 1998
561 - Bug fixes in Bio::Tools::Blast modules, version 0.072
562 (see Bio::Tools::Blast::CHANGES).
563 - Compile/SW/Makefile.PL now removes *.o and *.a files
566 0.04 Tue Dec 8 07:49:19 1998
567 - Lots of new modules added including:
568 * Ewan Birney's Bio::SimpleAlign.pm, Bio::Tools::AlignFactory.pm,
569 and Bio/Compile directory containing XS-linked C code for
570 creating Smith-Waterman sequence alignments from within Perl.
571 * Steve Chervitz's Blast distribution has been incorporated.
572 * Georg Fuellen's Bio::UnivAln.pm for multiple alignment objects.
573 - Bio/examples directory for demo scripts for all included modules.
574 - Bio/t directory containing test suit for all included modules.
575 - For changes specific to the Blast-related modules prior to
576 incorporation in this central distribution, see the CHANGES
577 file in the Bio/Tools/Blast directory.
579 0.01 Tue Sep 8 14:23:22 1998
580 - original version from central CVS tree; created by h2xs 1.18