1 ---------------------------------------------------------
2 Revision history for BioPerl core modules
3 ---------------------------------------------------------
4 The comprehensive history and ongoing development of BioPerl:
6 http://github.com/bioperl/bioperl-live
8 Some of that history is also highlighted on our wiki:
10 http://www.bioperl.org/wiki/Change_log
11 http://www.bioperl.org/wiki/History_of_BioPerl
13 Bugs and requested features list:
15 https://github.com/bioperl/bioperl-live/issues
17 CPAN releases are branched from 'master'.
18 ---------------------------------------------------------
23 * Minor fixes in Bio::Root::Build to deal with META.json/yml for CPAN indexing
29 * Bug/feature issue tracking has moved to GitHub Issues:
30 https://github.com/bioperl/bioperl-live/issues
31 * DB_File has been demoted from "required" to "recommended",
32 which should make easier for Windows users to install BioPerl
33 if they don't need that module.
37 * Bio::Search::HSP::GenericHSP
38 - Bug #3370, added a "posterior_string" method to retrieve the
39 posterior probability lines (PP) from HMMER3 reports [fjossandon]
40 - Added a "consensus_string" method to retrieve the consensus
41 structure lines (CS|RF) from HMMER2 and HMMER3 reports when available [fjossandon]
42 * Bio::SearchIO::hmmer2
43 - The number of identical and conserved residues are now calculated
44 directly from the homology line [fjossandon]
45 - Now the Query Length and Hit Length are reported when the alignment
46 runs until the end of the sequence/model ('.]' or '[]') [fjossandon]
47 - Implemented the capture of the consensus structure lines [fjossandon]
48 * Bio::SearchIO::hmmer3
49 - The number of identical and conserved residues are now calculated
50 directly from the homology line [fjossandon]
51 - Now the Hit Length is reported when the alignment runs until the end
52 of the sequence/model ('.]' or '[]') [fjossandon]
53 - Implemented the capture of the consensus structure lines [fjossandon]
54 - Implemented the capture of the posterior probability lines [fjossandon]
55 - Completed the development of NHMMER parsing, including alignments [fjossandon]
56 * Bio::SearchIO::SearchResultEventBuilder & Bio::SearchIO::IteratedSearchResultEventBuilder
57 - Feature #2615, moved "_init_parse_params", "max_significance, "signif",
58 "min_score", "min_bits, and "hit_filter" methods from
59 'IteratedSearchResultEventBuilder' to parent 'SearchResultEventBuilder'.
60 This means that the Bio::SearchIO->new() parameters '-signif', '-score',
61 '-bits' and '-hit_filter' will now work with other Bio::SearchIO formats
62 besides Blast, instead of being ignored. Added tests for all moved methods
63 using HMMER outputs and run the full test suite and everything pass [fjossandon]
64 * Bio::SeqIO::MultiFile
65 - Autodetection of file format [fangly]
66 * Bio::Tools::GuessSeqFormat:
67 - Format detection from non-seekable filehandles such as STDIN [fangly]
71 * Fix problems when using Storable as backend for cloning [v1.6.x branch, tsibley]
72 * Fix potential problems with Storable in Bio::DB::SeqFeature::Store [tsibley]
73 * SeqFeature::Lite: Fixed wrong strand when using "+", "-", or "." [nathanweeks]
74 * Abstract: Fixed ActivePerl incapability of removing temporary files
75 because of problems closing tied filehandles [fjossandon]
76 * IndexedBase: For Windows' ActivePerl, several LocalDB tests were failing
77 because ActivePerl were producing a ".index.pag" and ".index.dir"
78 files instead of a single ".index" file (like Strawberry Perl).
79 Now those temporary files are correctly considered and deleted. [fjossandon]
80 * Test files: Added missing module requirements (DB_File and Data::Stag)
81 to several tests files that were failing because those modules were
82 not present. Now those test files are correctly skipped instead. [fjossandon]
83 * Blast: Added support to changes in bl2seq from BLAST+ output, which
84 now uses "Subject=" instead of ">" to start hit lines [yschensandiego]
85 * Phylip: Return undef in "next_aln" at file end to avoid
86 an infinite loop [yschensandiego]
87 * HMMER3: When a hit description is too long, it is truncated in
88 the Scores table. In those cases, the more complete description from
89 the Annotation line (>>) will be used [fjossandon]
90 * GenericHSP: Added '.' to gap symbols in "_pre_gaps" (except for ERPIN),
91 since it is now used by HMMER3 format in alignments [fjossandon]
92 * GenericHit: Changed "frac_aligned_query" and "frac_aligned_hit"
93 to return undef if the query/hit length is unknown (like in some
94 HMMER outputs), to avoid division by 0 crashes. Also "query_length"
95 now is set to 0 if its undefined, to be consistent with hit "length" [fjossandon]
96 * HMMER: fixed many bugs in the parsing of Hmmer2 and Hmmer3 outputs,
97 added support to multi-query reports, reduced code redundancy,
98 and eliminated the automatic removal of hits below "inclusion threshold" [fjossandon]
99 * [3369] - Fixed reported bugs in parse from HMMSEARCH3 reports [fjossandon]
100 * [3446] - Fixed wrong marker position in Bio::Map::Physical [fjossandon]
101 * [3455] - Fixed wrong print of DBLink in Genbank file [bosborne]
102 * Fixed some Bio::Root::Utilities subroutines [fjossandon]
103 * Double-quotes on paths are needed in some places [fjossandon]
104 * [3453] - Allow multiple homologies and products in Entrezgene [fjossandon]
105 * Use "NUL" instead of"/dev/null" when running in Windows [fjossandon]
106 * Updated all files from Bio-Root, Bio-Coordinate and Bio-SearchIO-blastxml
107 with the latest changes made in their own repositories [fjossandon]
108 * General synching of files with the master branch [fjossandon]
109 * Fixed tests failing in Windows because of using Linux commands [fjossandon]
110 * Closed many open filehandles that prevented temporary files deletion [fjossandon]
111 * Fixed broken MeSH parser [fjossandon]
112 * Fixed missing detection of format in SeqIO when given a -string [fangly]
116 * Major Windows support updates! [fjossandon]
117 * MAKER update to allow for stricter standard codon table [cjfields]
118 * Better support for circular sequences [fjossandon]
119 * Fixes for some complex location types [fjossandon]
120 * Address CONTIG bug in GenBank format, bug #3448 [cjfields]
121 * Fix bug #2978 related to BLAST report type [fjossandon]
122 * Deobfuscator fixes [DaveMessina]
126 * Address CPAN test failures [cjfields]
127 * Add BIOPROJECT support for Genbank files [hyphaltip]
128 * Better regex support for HMMER3 output [bosborne]
132 * Minor update to address CPAN test failures
136 * Remove Bio::Biblio and related files [carandraug]
137 - this cause version clashes with an independently-released
138 version of Bio::Biblio
144 * Hash randomization fixes for perl 5.18.x
145 - Note: at least one module (Bio::Map::Physical) still has a failing test;
146 this is documented in bug #3446 and has been TODO'd; we will be pulling
147 Bio::Map and similar modules out of core into separate distributions in the
148 1.7.x release series [cjfields]
152 * Bio::Seq::SimulatedRead
153 - New module to represent reads taken from other sequences [fangly]
155 - Support of Clone::Fast as a faster cloning alternative [fangly]
157 - Moved the format() and variant() methods from Bio::*IO modules to
158 Bio::Root::IO [fangly]
159 - Can now use format() to get the type of IO format in use [fangly]
161 - New regexp() method to create regular expressions from IUPAC sequences
163 * Bio::SeqFeature::Primer and Bio::Seq::PrimedSeq:
164 - Code refresh [fangly]
166 - Added support for the Greengenes and Silva taxonomies [fangly]
167 * Bio::Tree::TreeFunctionsI
168 - get_lineage_string() represents a lineage as a string [fangly]
169 - add_trait() returns instead of reporting an error when the column
170 number is exceeded in add_trait() [fangly]
171 - Option to support tree leaves without trait [fangly]
172 - Allow ID of 0 in trait files [fangly]
173 * Bio::DB::Taxonomy::list
174 - Misc optimizations [fangly]
175 - Option -names of get_taxon() to help with ambiguous taxa [fangly]
176 * Bio::DB::Taxonomy::*
177 - get_num_taxa() returns the number of taxa in the database [fangly]
178 * Bio::DB::Fasta and Bio::DB::Qual
179 - support indexing an arbitrary list of files [fangly]
180 - user can supply an arbitrary index file name [fangly]
181 - new option to remove index file at the end [fangly]
183 - now handles IUPAC degenerate residues [fangly]
184 * Bio::PrimarySeq and Bio::PrimarySeqI
185 - speed improvements for large sequences [Ben Woodcroft, fangly]
187 - tightened and optimized quality string validation [fangly]
189 - new method and option 'block', to create FASTA output with space
190 intervaled blocks (similar to genbank or EMBL) has been implemented.
191 - package variables $WIDTH and $DEFAULT_SEQ_ID_TYPE have been removed
192 in favour of the methods 'width' and 'preferred_id_type` respectively.
194 - moved from bioperl-live into the separate distribution Bio-FeatureIO
195 * Bio::SeqFeature::Annotated
196 - moved from bioperl-live into the separate distribution Bio-FeatureIO
197 * Bio::Cluster::SequenceFamily
198 - improved performance when using get_members with overlapping multiple
200 * Bio::SearchIO::hmmer3
201 - now supports nhmmer [bosborne]
205 * [3302] Fixes bug in Bio::SearchIO::hmmer2.pm to correctly parse
206 multi-query hmmer output [Francisco J. Ossandon, Paul Cantalupo]
207 * [3421] Fixes bug in Bio::SearchIO::hmmer2.pm to correctly parse an HSP
208 with a line full of dashes [Francisco J. Ossandon, Paul Cantalupo]
209 * [3298] Fix bug in Bio::SearchIO::blast.pm where algorithm version
210 information was lost in a multi-result blast file [Paul Cantalupo]
211 * [3343] Fix bug in Bio::SearchIO::blasttable.pm to correctly calculate
212 total gaps [Paul Cantalupo]
213 * [3375] Fix DBLINK parsing bug in Bio::SeqIO::genbank.pm [Paul Cantalupo]
214 * [3376] Fix bug in Bio::SearchIO::hmmer2.pm to correctly handle case
215 when end of domain indicator is split across lines [Paul Cantalupo]
216 * [3240] Bio::AlignIO::stockholm now parses simple sequences [Bernd Web,
218 * [3237] Bio::DB::Fasta now allows blank lines between sequences, catches
219 instances where blank lines are within sequences [cjfields]
220 * Bio::DB::Fasta reports correct alphabet for files with multiple sequence
222 * Bio::DB::Fasta rev-comps sequences other than DNA properly [fangly]
223 * [3238] Fixes for Bio::DB::SeqFeature::Store::DBI::Pg [Thomas Burkhard,
225 * Various fixes for Stockholm file indexing and processing [bosborne]
226 * Fix edge case in FASTQ parsing where sequence of length 1 and qual of 0
227 breaks parsing [cjfields]
228 * Fix case where Bio::Seq::Meta* objects with no meta information could not
229 be reverse-complemented [fangly]
230 * Fix bug for fields without aliases in Bio::DB::Query::HIVQuery [fangly]
231 * Fix Bio::PopGen::IO::phase: sort values lexically instead of numerically
232 when unsure that values will be numerical [fangly]
233 * Fix undef warnings in Bio::SeqIO::embl [fangly]
234 * Fix undef warnings in Bio::DB::Fasta and Bio::DB::Qual [fangly]
235 * Fix Bio::Tools::IUPAC should accept any sequence object [fangly]
236 * Fix for 'Inappropriate ioctl' in Bio::DB::Store::berkeleydb3 [Olivier
238 * Bio::SeqFeature::Generic SeqfeatureI compliance: methods primary_tag,
239 source_tag and display_name must return a string, not undef [fangly]
240 * Bio::SimpleAlign and Bio::Seq compliance with Bio::FeatureHolderI
241 add_SeqFeature takes a single argument [fangly]
242 * Use cross-platform filenames and temporary directory in
243 Bio::DB::Taxonomy::flatfile [fangly]
244 * Fix bug in Bio::DB::Taxonomy::list where taxa with no ancestors were not
245 properly identified as existing taxa in the database [fangly]
246 * Fix issue where a Bio::DB::Taxonomy::list object could not be created
247 without also passing a lineage to store [fangly]
248 * Prevent passing a directory to the gi2taxid option (-g) of
249 bp_classify_hits_kingdom.pl and remove an 'earlier declaration' warning
251 * Fixed bp_genbank2gff3.pl crash when missing source feature date [fangly]
252 * Bio::PrimarySeq constructor -direct works for -seq or -ref_to_seq [fangly]
253 * Bio::Cluster::SequenceFamily - checks if the sequence has a Bio::Species
254 object before trying to access, and no longer returns repeated sequences.
261 * Use of AcePerl is deprecated; Ace.pm isn't actively maintained, and
262 modules using Ace will also be deprecated [lds, cjfields]
263 * Minor bug fix release
264 * Bio::SeqIO::gbxml tests require XML::SAX [hartzell]
265 * Address Build.PL issues when DBI is not present [hartzell]
266 * Skip gbxml.t and Interpro tests when modules not installed [cjfields]
267 * Remove deprecated code for perl 5.14.0 compat [cjfields]
268 * Due to schema changes and lack of support for older versions, support
269 for NeXML 0.9 is only (very) partially implemented.
270 See: https://redmine.open-bio.org/issues/3207
274 * [3205] - small fix to Bio::Perl blast_sequence() to make compliant with
275 docs [genehack, cjfields]
276 * $VERSION for CPAN/cpanm-based installs was broken; force setting of
277 module version from dist_version (probably not the best way to do this,
278 but it seems to work) [rbuels, cjfields]
281 1.6.900 April 14, 201
285 * This will probably be the last release to add significant features to
286 core modules; subsequent releases will be for bug fixes alone.
287 We are planning on a restructuring of core for summer 2011, potentially
288 as part of the Google Summer of Code. This may become BioPerl 2.0.
289 * Version bump represents 'just prior to v 1.7'. We may have point
290 releases to deal with bugs, with increments of 1.6.901, 1.6.902, etc.
291 This code essentially is what is on the github master branch.
295 * Core code updated for perl 5.12.x [cjfields, Charle Tilford]
297 - major overhaul of Bio::Tree code by Greg Jordan, fixes several bugs
298 - removal of Scalar::Util::weaken code, which was causing odd headaches
299 with premature GC, memory leaks with perl 5.10.0, etc [cjfields]
300 * Bio::DB::SeqFeature bug fixes for GBrowse2 compatibility [lds, scottcain,
302 * Bio::SeqIO::msout, Bio::SeqIO::mbsout - parsers for ms and mbs
305 - bug 2515 - new contribution [Ryan Golhar, jhannah]
307 - support for reading Maq, Sam and Bowtie files [maj]
308 - support for reading 454 GS Assembler (Newbler) ACE files [fangly]
309 - bug 2483: support for writing ACE files [Joshua Udall, fangly]
310 - bug 2599: support DBLINK annotation in GenBank files [cjfields]
311 - bug 2726: reading/writing granularity: whole scaffold or one contig
312 at a time [Joshua Udall, fangly]
314 - Added parsing of xrefs to OBO files, which are stored as secondary
315 dbxrefs of the cvterm [Naama Menda]
316 - General Interpro-related code refactors [dukeleto, rbuels, cjfields]
317 * PAML code updated to work with PAML 4.4d [DaveMessina]
321 * [3198] - sort tabular BLAST hits by score [DaveMessina]
322 * [3196] - fix invalid metadata produced by latest Module::Build [cjfields]
323 * [3190] - RemoteBlast GAPCOSTS regex fix [Ali Walsh, cjfields]
324 * [3185] - Bio::Tools::SeqStats->get_mol_wt now gives correct MW
326 * [3178] - fix tr/// issue in Bio::Range [Andrew Conley, cjfields]
327 * [3172] - Bio::DB::Fasta - catch possibly bad FASTA files [cjfields]
328 * [3164] - TreeFunctionsI syntax bug [gjuggler]
329 * [3163] - AssemblyIO speedup [fangly]
330 * [3160] - Bio::SearchIO::Writer::TextResultWriter output [Paul Cantalupo,
332 * [3159] - add SwissPfam support to bp_index.PLS [hyphaltip]
333 * [3158] - fix EMBL file mis-parsing [cjfields]
334 * [3157] - Bio::Restriction::Analysis 'sizes' method fixed [Marc Perry,
336 * [3153] - fix SeqIO::swiss TagTree issues [Charles Tilford, cjfields]
337 * [3148] - URL change for UniProt [cjfields]
338 * [3145] - AXT off-by-1 error [Aaron Goodman, cjfields]
339 * [3136] - HMMer3 parser fixes [kblin]
340 * [3126] - catch description [Toshihiko Akiba]
341 * [3122] - Catch instances where non-seekable filehandles were being
342 seek'd w/o checking for status [Stefan Kirov, Roy Chaudhuri]
343 * [3121] - Bio::OntologyIO cannot parse the full InterPro XML file
344 [dukeleto, rbuels, cjfields]
345 * [3120] - bp_seqfeature_gff3.pl round-trip fixes [genehack, David Breimann,
347 * [3116,3117] - perl 5.12.x warnings fixed [cjfields, Charles Tilford]
348 * [3110] - Better 'namespace' support for bp_seqfeature_load.PLS [dbolser,
350 * [3107] - BLAST alignment column_from_residue_number() [cjfields]
351 * [3104] - Bio::Species single node hierarchies [Charles Tilford, cjfields]
352 * [3092, 3090] - parsing of BLAST HSP stats [Razi Khaja, cjfields]
353 * [3089] - HSPTableWriter missing methods [Robson de Souza, cjfields]
354 * [3086] - EMBL misparsing long tags [kblin, cjfields]
355 * [3085] - CommandExts and array of files [maj, hyphaltip]
356 * [3077] - Bio::SimpleAlign slice() now correctly computes seq coordinates
357 for alignment slices [Ha X. Dang, cjfields]
358 * [3076] - XMFA alignment strand wrong [Ha X., cjfields]
359 * [3073] - fix parsing of GenBank files from RDP [cjfields]
360 * [3068] - FASTQ parse failure with trailing 0 [cjfields]
361 * [3064] - All-gap midline BLAST report issues [cjfields]
362 * [3063] - BLASt report RID [Razi Khaja, cjfields]
363 * [3058] - SearchIO::fasta parsing [DaveMessina, cjfields]
364 * [3053] - LOCUS line formatting [M. Wayne, cjfields]
365 * [3039] - correct Newick output root node branch length [gjuggler,
367 * [3038] - SELEX alignment error [Bernd, cjfields]
368 * [3033] - PrimarySeq ID setting [Bernd, maj]
369 * [3032] - Fgenesh errors [Wes Barris, hyphaltip]
370 * [3034] - AlignIO::clustal output [Bernd, DaveMessina]
371 * [3031] - Parse algorithm ref for BLAST [Razi Khaja, cjfields]
372 * [3028] - Bio::TreeIO::nexus and FigTree compat [Kevin Balbi, cjfields]
373 * [3025] - Bio::SeqIO::embl infinite loop [Adam Sjøgren, cjfields]
374 * [3040, 3023, 2974, 2921, 2753, 2636, 2482] - PAML parser fixed, works with
375 PAML 4.4d [DaveMessina]
376 * [3015, 3022] - Bio::Restriction withrefm regexp [Emmanuel Quevillon,
378 * [3020] - GFF3Loader alias attribute [Nathan Weeks, cjfields]
379 * [3018, 3019, 3021] - gmap_f9 parsing [Kiran Mukhyala, cjfields]
380 * [3017] - using threads with Bio::DB::GenBank [cjfields]
381 * [3012] - Bio::Root::HTTPget fixes [maj, cjfields]
382 * [3011] - namespace support for SF::Store::DBI::Pg [Adam Witney, cjfields]
383 * [3002] - Bio::DB::EUtilities NCBI policy updates [cjfields]
384 * [3001] - seq identifier '0' dropped with FASTA [Michael Kuhn, maj]
385 * [2984] - let LocatableSeq decide on length of phylip aln [Adam Witney,
387 * [2983] - fix score/percent ID mixup [Alexie Papanicolaou]
388 * [2977] - TreeIO issues [DaveMessina]
389 * [2959] - Bio::SeqUtils->revcom_with_features [Roy Chaudhuri, maj]
390 * [2944] - Bio::Tools::GFF score [cjfields]
391 * [2942] - correct MapTiling output [maj]
392 * [2939] - PDB residue insertion codes [John May, maj]
393 * [2930] - PrimarySeqI term symbol [Adam Sjøgren, maj]
394 * [2928] - GuessSeqFormat raw [maj]
395 * [2926] - Bio:Tools::TandemRepeatsFinder seq_id [takadonet, cjfields]
396 * [2922] - open() directive issue [cjfields]
397 * [2915] - GenBank parser infinite loop [Francisco Ossandon, cjfields]
398 * [2901] - DNAStatistics div by zero error [Janet Young, cjfields]
399 * [2899] - SeqFeature::Store host issues [lstein, dbolser]
400 * [2897] - Add a "mask_below_threshold" method to Seq::Quality [dbolser,
402 * [2881] - .scf files don't' roundtrip [Adam Sjøgren, cjfields]
403 * [2876] - CDD search with RemoteBlast [Malcolm Cook]
404 * [2863] - Root::IO::_initialize_io causes crash [rbuels, maj, DaveMessina]
405 * [2845] - Bio::Seq::Quality gives seq with no ID [Tristan Lefebure, cjfields]
406 * [2843] - FeatureIO BED to GFF fails w/ no phase [cassjm cjfields]
407 * [2773] - Bio::Tree::Node premature GC [Morgan Price, cjfields]
408 * [2764] - add ID Tracker helper for SwissProt [heikki, cjfields]
409 * [2758] - Bio::AssemblyIO ace problems [fangly]
410 * [2744] - Bio::LocatableSeq::end [Bernd, cjfields]
411 * [2726] - ace file IO [Josh, fangly]
412 * [2700] - Refactor Build.PL [cjfields]
413 * [2673] - addition of simple Root-based clone() method [cjfields]
414 * [2648] - Bio::Assembly::Scaffold->get_all_seq_ids [dbolser, fangly]
415 * [2599] - support for DBLINK annotation in GenBank files [cjfields]
416 * [2594] - Bio::Species memory leak [cjfields]
417 * [2515] - GenBank XML parser [jhannah]
418 * [2499] - Method "pi" in package Bio::PopGen::Statistics [hyphaltip]
419 * [2483] - Bio::Assembly::IO::ace write_assembly implemented [fangly]
420 * [2350] - ID consistency btwn Bio::SeqI, Bio::Align::AlignI [fangly,
422 * [1572] - no docs Bio::Location::Simple/Atomic::trunc [hyphaltip]
426 * Bio::Expression modules - these were originally designed to go with the
427 bioperl-microarray suite of tools, however they have never been completed
428 and so have been removed from the distribution. The original code has
429 been moved into the inactive bioperl-microarray suite. [cjfields]
433 * Repository moved from Subversion (SVN) to
434 http://github.com/bioperl/bioperl-live [cjfields]
435 * Bug database has moved to Redmine (https://redmine.open-bio.org)
436 * Bio::Micrarray - the tools developed for ReSeq chip analysis by Marian
437 Thieme have been moved to their own distribution (Bio-Microarray).
440 1.6.1 Sept. 29, 2009 (point release)
441 * No change from last alpha except VERSION and doc updates [cjfields]
443 1.6.0_6 Sept. 27, 2009 (sixth 1.6.1 alpha)
444 * Fix for silent OBDA bug related to FASTA validation [cjfields]
446 1.6.0_5 Sept. 27, 2009 (fifth 1.6.1 alpha)
447 * Possible fix for RT 49950 (Strawberry Perl installation) [cjfields]
448 * [RT 50048] - removed redundant VERSION, which was borking CPANPLUS
450 * BioPerl.pod -> BioPerl.pm (Perl Best Practices) [cjfields]
452 1.6.0_4 Sept. 25, 2009 (fourth 1.6.1 alpha)
453 * WinXP test fixes [cjfields, maj]
454 * BioPerl.pod added for descriptive information, fixes CPAN indexing
456 * Minor doc fixes [cjfields]
458 1.6.0_3 Sept. 22, 2009 (third 1.6.1 alpha)
459 * Fix tests failing due to merging issues [cjfields]
460 * More documentation updates for POD parsing [cjfields]
462 1.6.0_2 Sept. 22, 2009 (second 1.6.1 alpha)
464 - fix YAML meta data generation [cjfields]
466 1.6.0_1 Sept. 15, 2009 (first 1.6.1 alpha)
467 * Bio::Align::DNAStatistics
468 - fix divide by zero problem [jason]
470 - bug 2813 - fix faulty logic to detect end-of-stream [cjfields]
471 * Bio::AlignIO::stockholm
472 - bug 2796 - fix faulty logic to detect end-of-stream [cjfields]
473 * Bio::Assembly::Tools::ContigSpectrum
474 - function to score contig spectrum [fangly]
475 * Bio::DB::EUtilities
476 - small updates [cjfields]
478 - berkeleydb database now autoindexes wig files and locks correctly
481 - various small updates for stability; tracking changes to LANL
482 database interface [maj]
483 * Bio::DB::SeqFeature (lots of updates and changes)
484 - add Pg, SQLite, and faster BerkeleyDB implementations [lstein, scain]
485 - bug 2835 - patch [Dan Bolser]
486 - bug RT 44535 - patch FeatureFileLoader [Cathy Gresham]
488 - bug 2764 - idtracker() method [cjfields, courtesy Neil Saunders]
489 * Bio::Factory::FTLocationFactory
490 - mailing list bug fix [cjfields]
492 - performance work on column_from_residue_number [hartzell]
493 * Bio::Matrix::IO::phylip
494 - bug 2800 - patch to fix phylip parsing [Wei Zou]
496 - Google Summer of Code project from Chase Miller - parsers for Nexml
497 file format [maj, chmille4]
499 - Make Individual, Population, Marker objects AnnotatableI [maj]
500 - simplify LD code [jason]
502 - deal with empty intersection [jason]
504 - significant overhaul of Bio::Restriction system: complete support for
505 external and non-palindromic cutters. [maj]
507 - CPANPLUS support, no automatic installation [sendu]
509 - allow IO::String (regression fix) [cjfields]
510 - catch unintentional undef values [cjfields]
511 - throw if non-fh is passed to -fh [maj]
512 * Bio::Root::Root/RootI
513 - small debugging and core fixes [cjfields]
515 - bug RT 48813 - fix for Strawberry Perl bug [kmx]
516 * Bio::Root::Utilities
517 - bug 2737 - better warnings [cjfields]
519 - tiling completely refactored, HOWTO added [maj]
520 NOTE : Bio::Search::Hit::* classes do not use this code directly; we
521 will deprecate usage of the older tiling code in the next BioPerl
523 - small fixes [cjfields]
525 - Infernal 1.0 output now parsed [cjfields]
526 - new parser for gmap -f9 output [hartzell]
527 - bug 2852 - fix infinite loop in some output [cjfields]
528 - blastxml output now passes all TODO tests [cjfields]
529 - bug 2346, 2850 - psl and exonerate parsing fixes [rbuels, jhannah, bvecchi, YAPC hackathon]
530 - RT 44782 - GbrowseGFF writer now catches evalues [Allen Day]
531 - bug 2575 - add two columns of additional output to HSPTableWriter [cjfields]
532 * Bio::Seq::LargePrimarySeq
533 - delete tempdirs [cjfields]
534 - bug fixes [rbuels, jhannah, bvecchi, YAPC hackathon]
536 - extract regions based on quality threshold value [Dan Bolser, heikki]
537 - bug 2847 - resolve threshold issue (rbuels, jhannah, bvecchi)
538 * Bio::SeqFeature::Lite
539 - various Bio::DB::SeqFeature-related fixes [lstein]
540 * Bio::SeqFeature::Tools::TypeMapper
541 - additional terms for GenBank to SO map [scain]
542 * Bio::SeqIO::chadoxml
543 - bug 2785 - patch to get this working for bp_seqconvert [cjfields]
545 - support for CDS records [dave_messina, Sylvia]
547 - complete refactoring to handle all FASTQ variants, perform validation,
548 write output. API now conforms with other Bio* parsers and the rest of
549 Bio::SeqIO (e.g. write_seq() creates fastq output, not fasta output).
551 * Bio::SeqIO::genbank
552 - bug 2784 - fix DBSOURCE issue [Phillip Garland]
553 - bug RT 44536 - support for UniProt/UniProtKB tests [cjfields]
554 * Bio::SeqIO::largefasta
555 - parser returns a Bio::Seq::LargePrimarySeq [jhannah]
557 - add option for 'single' and 'multiple'
559 - bug 2881 - fix scf round-tripping [Adam Søgren]
561 - bug 2766, 2810 - copy over tags from features, doc fixes [David
564 - bug 2793 - patch for add_seq index issue [jhannah, maj]
565 - bug 2801 - throw if args are required [cjfields]
566 - bug 2805 - uniq_seq returns SimpleAlign and hash ref of sequence types
567 [Tristan Lefebure, maj]
568 - bug fixes from YAPC hackathon [rbuels, jhannah, bvecchi]
569 - fix POD and add get_SeqFeatures filter [maj]
570 * Bio::Tools::dpAlign
571 - add support for LocatableSeq [ymc]
572 - to be moved to a separate distribution [cjfields, rbuels]
573 * Bio::Tools::EUtilities
574 - fix for two bugs from mail list [Adam Whitney, cjfields]
575 - add generic ItemContainerI interface for containing same methods
578 - fix up code, add more warnings [cjfields]
579 - to be moved to a separate distribution [cjfields, rbuels]
580 * Bio::Tools::Primer3
581 - bug 2862 - fenceposting issue fixed [maj]
582 * Bio::Tools::Run::RemoteBlast
583 - tests for remote RPS-BLAST [mcook]
584 * Bio::Tools::SeqPattern
585 - bug 2844 - backtranslate method [rbuels, jhannah, bvecchi]
586 * Bio::Tools::tRNAscanSE
587 - use 'gene' and 'exon' for proper SO, ensure ID is unique [jason]
589 - bug 2456 - fix reroot_tree(), added create_node_on_branch() [maj]
590 * Bio::Tree::Statistics
591 - several methods for calculating Fitch-based score, internal trait
592 values, statratio(), sum of leaf distances [heikki]
594 - bug 2869 - add docs indicating edge case where nodes can be
595 prematurely garbage-collected [cjfields]
596 - add as_text() function to create Tree as a string in specified format
598 * Bio::Tree::TreeFunctionsI
599 - bug 2877 - fix bug where bootstrap assigned to the wrong node [Tristan
601 * Bio::TreeIO::newick
602 - fix small semicolon issue [cjfields]
604 - update to bp_seqfeature_load for SQLite [lstein]
605 - hivq.pl - commmand-line interface to Bio::DB::HIV [maj]
606 - fastam9_to_table - fix for MPI output [jason]
607 - gccalc - total stats [jason]
609 - POD cleanup re: FEEDBACK section [maj, cjfields]
610 - cleanup or fix dead links [cjfields]
611 - Use of no_* methods (indicating 'number of something') is deprecated
612 in favor of num_* [cjfields]
613 - lots of new tests for the above bugs and refactors [everyone!]
614 - new template for Komodo text editor [cjfields]
617 * Feature/Annotation rollback
618 - Problematic changes introduced prior to the 1.5 release have been
619 rolled back. These changes led to subtle bugs involving operator
620 overloading and interface methods.
621 - Behavior is very similar to that for BioPerl 1.4, with tag values
622 being stored generically as simple scalars. Results in a modest
625 - Split into a separate distribution on CPAN, primarily so development
626 isn't reliant on a complete BioPerl release.
627 - Bio::Graphics::Pictogram has been renamed to Bio::Draw::Pictogram but
628 is only available via Subversion (via bioperl-live main trunk)
630 - Common test bed for all BioPerl modules
632 - Common Module::Build-based subclass for all BioPerl modules
633 * Bio::DB::EUtilities
634 - Complete refactoring to split up parsing (Bio::Tools::EUtilities),
635 parameter handling (Bio::Tools::EUtilities::EUtilParameters),
636 and user agent request posting and retrieval
637 * Test implementation and reorganization
638 - Tests have been reorganized into groups based on classes or use
640 - Automated test coverage is now online:
641 http://www.bioperl.org/wiki/Test_Coverage
642 - After this release, untested modules will be moved into a
643 separate developer distribution until tests can be derived.
644 Also, new modules to be added are expected to have a test suite
645 and adequate test coverage.
647 1.5.2 Developer release
649 Full details of changes since 1.5.1 are available online at:
650 http://www.bioperl.org/wiki/Change_log
651 The following represents a brief overview of the most important changes.
654 - Overhaul. Brand new system fully allows markers to have multiple
655 positions on multiple maps, and to have relative positions. Should be
659 - This module and all the modules in the Taxonomy directory now
660 deprecated in favour of Bio::Taxon and Bio::Tree::Tree
665 * get_Taxonomy_Node() eventually to be deprecated, renamed get_taxon().
667 * New methods ancestor(), each_Descendent() and _handle_internal_id().
669 * Allows for different database modules to create Bio::Taxon objects
670 with the same internal id when the same taxon is requested from each.
673 * get_Children_Taxids() is deprecated, superceded by each_Descendent().
675 * No longer includes the fake root node 'root'; there are multiple roots
676 now (10239, 12884, 12908, 29384 and 131567). Consistent with entrez.pm
679 * get_node() has new option -full
681 * Caches data retrieved from website
684 - Now a Bio::Taxon. Carries out the species name -> specific name munging
685 that Bio::DB::Taxonomy modules and SeqIO modules used to do, for
686 backward compatability in species() method.
688 o Bio::Search and Bio::SearchIO
689 - Overhaul. The existing system has been sped up via some minor changes
690 (mostly gain-of-function to the API). Bio::PullParserI is introduced
691 as a potential eventual replacment for the existing system, though as
692 yet only a Hmmpfam parser exists written using it.
695 1.5.1 Developer release
697 o Major problem with how Annotations were written out with
698 Bio::Seq is fixed by reverting to old behavior for
699 Bio::Annotation objects.
704 * bug #1871; REFLOOP' parsing loop, I changed the pattern to
705 expect at l east 9 spaces at the beginning of a line to
706 indicate line wrapping.
708 * Treat multi-line SOURCE sections correctly, this defect broke
709 both common_name() and classification()
711 * parse swissprot fields in genpept file
713 * parse WGS genbank records
716 * Changed regexp for ID line. The capturing parentheses are
717 the same, the difference is an optional repeated-not-semi-
718 colon expression following the captured \S+. This means the
719 regexp works when the division looks like /PRO;/ or when the
720 division looks like /ANG ;/ - the latter is from EMBL
723 * fix ID line parsing: the molecule string can have spaces in
724 it. Like: "genomic DNA"
726 - swiss.pm: bugs #1727, #1734
729 * Added parser for entrezgene ASN1 (text format) files.
730 Uses Bio::ASN1::EntrezGene as a low level parser (get it from CPAN)
734 - maf.pm coordinate problem fixed
736 o Bio::Taxonomy and Bio::DB::Taxonomy
738 - Parse NCBI XML now so that nearly all the taxonomy up-and-down
739 can be done via Web without downloading all the sequence.
741 o Bio::Tools::Run::RemoteBlast supports more options and complies
742 to changes to the NCBI interface. It is reccomended that you
743 retrieve the data in XML instead of plain-text BLAST report to
744 insure proper parsing and retrieval of all information as NCBI
745 fully expects to change things in the future.
747 o Bio::Tree and Bio::TreeIO
749 - Fixes so that re-rooting a tree works properly
751 - Writing out nhx format from a newick/nexus file will properly output
752 bootstrap information. The use must move the internal node labels over
754 for my $node ( grep { ! $_->is_Leaf } $tree->get_nodes ) {
755 $node->bootstrap($node->id);
758 - Nexus parsing is much more flexible now, does not care about
761 - Cladogram drawing module in Bio::Tree::Draw
763 - Node height and depth now properly calculated
765 - fix tree pruning algorithm so that node with 1 child gets merged
767 o Graphics tweaks. Glyph::xyplot improved. Many other small-medium sized
768 bugs and improvements were added, see Gbrowse mailing list for most of
771 o Bio::DB::GFF partially supports GFF3. See information about
772 gff3_munge flag in scripts/Bio-DB-GFF/bulk_load_gff.pl.
774 o Better location parsing in Bio::Factory::FTLocationFactory -
775 this is part of the engine for parsing EMBL/GenBank feature table
776 locations. Nested join/order-by/complement are allowed now
778 o Bio::PrimarySeqI->translate now takes named parameters
780 o Bio::Tools::Phylo::PAML - parsing RST (ancestral sequence
781 reconstruction) is now supported. Parsing different models and
782 branch specific parametes are now supported.
784 o Bio::Factory::FTLocationFactory - parse hierarchical locations
787 o Bio::Matrix::DistanceMatrix returns arrayrefs instead of arrays
788 for getter/setter functions
792 - blast bug #1739; match scientific notation in score
793 and possible e+ values
795 - blast.pm reads more WU-BLAST parameters and parameters, match
796 a full database pathname,
798 - Handle NCBI WEB and newer BLAST formats specifically
799 (Query|Sbjct:) match in alignment blocks can now be (Query|Sbjct).
801 - psl off-by-one error fixed
803 - exonerate parsing much improved, CIGAR and VULGAR can be parsed
804 and HSPs can be constructed from them.
806 - HSPs query/hit now have a seqdesc field filled out (this was
807 always available via $hit->description and
808 $result->query_description
810 - hmmer.pm can parse -A0 hmmpfam files
812 - Writer::GbrowseGFF more customizeable.
814 o Bio::Tools::Hmmpfam
815 make e-value default score displayed in gff, rather than raw score
816 allow parse of multiple records
819 1.5 Developer release
821 o Bio::Align::DNAStatistics and Bio::Align::ProteinStatistics
822 provide Jukes-Cantor and Kimura pairwise distance methods,
825 o Bio::AlignIO support for "po" format of POA, and "maf";
826 Bio::AlignIO::largemultifasta is a new alternative to
827 Bio::AlignIO::fasta for temporary file-based manipulation of
828 particularly large multiple sequence alignments.
830 o Bio::Assembly::Singlet allows orphan, unassembled sequences to
831 be treated similarly as an assembled contig.
833 o Bio::CodonUsage provides new rare_codon() and probable_codons()
834 methods for identifying particular codons that encode a given
837 o Bio::Coordinate::Utils provides new from_align() method to build
838 a Bio::Coordinate pair directly from a
839 Bio::Align::AlignI-conforming object.
841 o Bio::DB::Biblio::eutils is a class for querying NCBI's Eutils.
842 Send a Pubmed, Pubmed Central, Entrez, or other query to NCBI's
843 web service using standard Pubmed query syntax, and retrieve
846 o Bio::DB::GFF has various sundry bug fixes.
848 o Bio::FeatureIO is a new SeqIO-style subsystem for
849 writing/reading genomic features to/from files. I/O classes
850 exist for BED, GTF (aka GFF v2.5), and GFF v3. Bio::FeatureIO
851 classes only read/write Bio::SeqFeature::Annotated objects.
852 Notably, the GFF v3 class requires features to be typed into the
855 o Bio::Graph namespace contains new modules for manipulation and
856 analysis of protein interaction graphs.
858 o Bio::Graphics has many bug fixes and shiny new glyphs.
860 o Bio::Index::Hmmer and Bio::Index::Qual provide multiple-file
861 indexing for HMMER reports and FASTA qual files, respectively.
863 o Bio::Map::Clone, Bio::Map::Contig, and Bio::Map::FPCMarker are
864 new objects that can be placed within a Bio::Map::MapI-compliant
865 genetic/physical map; Bio::Map::Physical provides a new physical
866 map type; Bio::MapIO::fpc provides finger-printed clone mapping
869 o Bio::Matrix::PSM provide new support for postion-specific
870 (scoring) matrices (e.g. profiles, or "possums").
872 o Bio::Ontology::Ontology and Bio::Ontology::Term objects can now
873 be instantiated without explicitly using Bio::OntologyIO. This
874 is possible through changes to Bio::Ontology::OntologyStore to
875 download ontology files from the web as necessary. Locations of
876 ontology files are hard-coded into
877 Bio::Ontology::DocumentRegistry.
879 o Bio::PopGen includes many new methods and data types for
880 population genetics analyses.
882 o New constructor to Bio::Range, unions(). Given a list of
883 ranges, returns another list of "flattened" ranges --
884 overlapping ranges are merged into a single range with the
885 mininum and maximum coordinates of the entire overlapping group.
887 o Bio::Root::IO now supports -url, in addition to -file and -fh.
888 The new -url argument allows one to specify the network address
889 of a file for input. -url currently only works for GET
890 requests, and thus is read-only.
892 o Bio::SearchIO::hmmer now returns individual Hit objects for each
893 domain alignment (thus containing only one HSP); previously
894 separate alignments would be merged into one hit if the domain
895 involved in the alignments was the same, but this only worked
896 when the repeated domain occured without interruption by any
897 other domain, leading to a confusing mixture of Hit and HSP
900 o Bio::Search::Result::ResultI-compliant report objects now
901 implement the "get_statistics" method to access
902 Bio::Search::StatisticsI objects that encapsulate any
903 statistical parameters associated with the search (e.g. Karlin's
904 lambda for BLAST/FASTA).
906 o Bio::Seq::LargeLocatableSeq combines the functionality already
907 found in Bio::Seq::LargeSeq and Bio::LocatableSeq.
909 o Bio::SeqFeature::Annotated is a replacement for
910 Bio::SeqFeature::Generic. It breaks compliance with the
911 Bio::SeqFeatureI interface because the author was sick of
912 dealing with untyped annotation tags. All
913 Bio::SeqFeature::Annotated annotations are Bio::AnnotationI
914 compliant, and accessible through Bio::Annotation::Collection.
916 o Bio::SeqFeature::Primer implements a Tm() method for primer
917 melting point predictions.
919 o Bio::SeqIO now supports AGAVE, BSML (via SAX), CHAOS-XML,
920 InterProScan-XML, TIGR-XML, and NCBI TinySeq formats.
922 o Bio::Taxonomy::Node now implements the methods necessary for
923 Bio::Species interoperability.
925 o Bio::Tools::CodonTable has new reverse_translate_all() and
926 make_iupac_string() methods.
928 o Bio::Tools::dpAlign now provides sequence profile alignments.
930 o Bio::Tools::GFF now parses GFF version 2.5 (a.k.a. GTF).
932 o Bio::Tools::Fgenesh, Bio::Tools::tRNAscanSE are new report
935 o Bio::Tools::SiRNA includes two new rulesets (Saigo and Tuschl)
936 for designing small inhibitory RNA.
938 o Bio::Tree::DistanceFactory provides NJ and UPGMA tree-building
939 methods based on a distance matrix.
941 o Bio::Tree::Statistics provides an assess_bootstrap() method to
942 calculate bootstrap support values on a guide tree topology,
943 based on provided bootstrap tree topologies.
945 o Bio::TreeIO now supports the Pagel (PAG) tree format.
951 o Improvements to Bio::AlignIO::nexus for parsing TreeBase nexus files
953 o Bio::Graphics will work with gd1 or gd2
956 - hmmer.pm Better hmmpfam parsing, fix bug for small number of alignment outputs
958 - blast.pm Parse multi-line query fields properly
959 - small speed improvements to blasttable.pm and others
961 o Bio::DB::Taxonomy has better support for hierarchy traversal so that
962 Bio::Taxonomy::Node can be as simple as Bio::Species object while still
963 supporting more complex queries
966 1.4. Stable major release
968 Since initial 1.2.0, 3000 separate changes have been made to make this release.
970 o installable scripts
972 o global module version from Bio::Root:Version
975 - major improvements; SVG support
978 - population genetics
979 - support several population genetics types of questions.
980 - Tests for statistical neutrality of mutations
981 (Fu and Li's D/F, Tajima's D) are in Bio::PopGen::Statistics.
982 Tests of population structure (Wright's F-statistic: Fst) is in
983 Bio::PopGen::PopStats. Calculating composite linkage
984 disequilibrium (LD) is available in Bio::PopGen::Statistics as
986 - Bio::PopGen::IO for reading in prettybase (SeattleSNPs)
987 and csv (comma delimited formatted) data.
989 - a directory for implementing population simulations has
990 been added Bio::PopGen::Simulation and 2 simulations - a
991 Coalescent and a simple single-locus multi-allele genetic drift
992 simulation have been provided. This replaces the code in
993 Bio::Tree::RandomTree which has been deprecated until proper
994 methods for generating random phylogenetic trees are
998 - new restrion analysis modules
1000 o Bio::Tools::Analysis
1001 - web based DNA and Protein analysis framework and several
1005 - per residue annotable sequences
1008 - Bio::Matrix::PSM - Position Scoring Matrix
1009 - Bio::Matrix::IO has been added for generalized parsing of
1010 matrix data. Matrix::IO::scoring and Matrix::IO::phylip are
1011 initial implementations for parsing BLOSUM/PAM and Phylip
1012 Distance matricies respectively. A generic matrix
1013 implementation for general use was added in
1014 Bio::Matrix::Generic.
1021 o Bio::Tools::SiRNA, Bio::SeqFeature::SiRNA
1022 - small inhibitory RNA
1024 o Bio::SeqFeature::Tools
1025 - seqFeature mapping tools
1026 - Bio::SeqFeature::Tools::Unflattener.pm
1027 -- deal with mapping GenBank feature collections into
1028 Chado/GFF3 processable feature sets (with SO term mappings)
1030 o Bio::Tools::dpAlign
1031 - pure perl dynamic programming sequence alignment
1034 o new Bio::SearchIO formats
1035 - axt and psl: UCSC formats.
1036 - blasttable: NCBI -m 8 or -m 9 format from blastall
1038 o new Bio::SeqIO formats
1039 - chado, tab, kegg, tigr, game
1040 - important fixes for old modules
1044 o improved Bio::Tools::Genewise
1046 o Bio::SeqIO now can recongnize sequence formats automatically from
1049 o new parsers in Bio::Tools:
1050 Blat, Geneid, Lagan, Mdust, Promoterwise, PrositeScan,
1052 o Bio::DB::Registry bugs fixed
1053 - BerkeleyDB-indexed flat files can be used by the OBDA system
1054 - Multiple seqdatabase.ini locations in OBDA_SEARCH_PATH are all
1055 used by the OBDA system
1057 o several new HOWTOs
1058 - SimpleWebAnalysis, Trees, Feature Annotation, OBDA Access, Flat
1061 o hundreds of new and improved files
1065 o Bio::Tree::AlleleNode has been updated to be a container of
1066 an Bio::PopGen::Individual object for use in the Coalescent simulations.
1071 1.2.3 Stable release update
1072 o Bug #1475 - Fix and add speedup to spliced_seq for remote location
1074 o Bug #1477 - Sel --> Sec abbreviation fixed
1075 o Fix bug #1487 where paring in-between locations when
1076 end < start caused the FTLocationFactory logic to fail.
1077 o Fix bug #1489 which was not dealing with keywords as an
1078 arrayref properly (this is fixed on the main trunk because
1079 keywords returns a string and the array is accessible via
1081 o Bio::Tree::Tree memory leak (bug #1480) fixed
1082 Added a new initialization option -nodelete which
1083 won't try and cleanup the containing nodes if this
1085 o Bug with parsing labeled nodes with Bio::TreeIO::newick fixed
1086 this was only present on the branch for the 1.2.1 and 1.2.2 series
1087 - Also merged main trunk changes to the branch which make
1088 newick -> nhx round tripping more effective (storing branch length
1089 and bootstrap values in same locate for NodeNHX and Node
1090 implementations.) Fixes to TreeIO parsing for labeled internal
1091 also required small changes to TreeIO::nhx. Improved
1092 tests for this module as well.
1094 - Fixed bugs in BLAST parsing which couldn't parse NCBI
1095 gapped blast properly (was losing hit significance values due to
1096 the extra unexpeted column).
1097 - Parsing of blastcl3 (netblast from NCBI) now can handle case of
1098 integer overflow (# of letters in nt seq dbs is > MAX_INT)
1099 although doesn't try to correct it - will get the negative
1100 number for you. Added a test for this as well.
1101 - Fixed HMMER parsing bug which prevented parsing when a hmmpfam report
1102 has no top-level family classification scores but does have scores and
1103 alignments for individual domains.
1104 - Parsing FASTA reports where ungapped percent ID is < 10 and the
1105 regular expression to match the line was missing the possibility of
1106 an extra space. This is rare, which is why we probably did not
1108 - BLAST parsing picks up more of the statistics/parameter fields
1109 at the bottom of reports. Still not fully complete.
1110 - SearchIO::Writer::HTMLResultWriter and TextResultWriter
1111 were fixed to include many improvements and added flexiblity
1112 in outputting the files. Bug #1495 was also fixed in the process.
1114 - Update for GFF3 compatibility.
1115 - Added scripts for importing from UCSC and GenBank.
1116 - Added a 1.2003 version number.
1119 - Added a 1.2003 version number.
1120 o SeqIO::swiss Bug #1504 fixed with swiss writing which was not
1121 properly writing keywords out.
1122 o Bio::SeqIO::genbank
1123 - Fixed bug/enhancement #1513 where dates of
1124 the form D-MMM-YYYY were not parsed. Even though this is
1125 invalid format we can handle it - and also cleanup the date
1126 string so it is properly formatted.
1127 - Bug/enhancement #1517 fixed so that SEGMENT line can be parsed
1128 and written with Genbank format. Similarly bug #1515 is fixed to
1129 parse in the ORIGIN text.
1130 o Bio::SeqIO::fasta, a new method called preferred_id_type allows you
1131 to specify the ID type, one of (accession accession.version
1132 display primary). See Bio::SeqIO::preferred_id_type method
1133 documentation for more information.
1134 o Unigene parsing updated to handle file format changes by NCBI
1136 1.2.2 Stable release update
1138 o A series of bug fixes of the Bio::OntologyIO dagflat-related parsers:
1139 - auto-discover ontology name
1140 - bug in parsing relationships when certain characters are in the term
1141 - fixed hard-coded prefix for term identifiers
1142 - various smaller issues
1144 o Fixed bug in Bio::Annotation::OntologyTerm of not implementing all
1145 of Bio::Ontology::TermI
1147 o brought the OBDA Registry code up to latest specs
1151 - accession number retrieval fixed
1153 o Bio::SearchIO::blast - fix bug #1443 (missing last hits), parse megablast
1155 o Bio::SearchIO::Writer::(HTML|Text)ResultWriter fix bugs #1458,
1156 #1459 which now properly report alignment start/end info
1157 for translated BLAST/FASTA searches.
1159 o Bio::TreeIO::newick can parse labeled internal nodes
1161 o Bio::Tools::BPbl2seq can properly report strand info for HSPs
1162 for BLASTX if if you provide -report_type => 'BLASTX' when
1163 initializing a BPbl2seq object. Bioperl 1.3 will have better
1164 support for bl2seq in the SearchIO system.
1166 o Bio::Root::IO support a -noclose boolean flag which will not
1167 close a filehandle upon object cleanup - useful when sharing
1168 a filehandle among objects. Additionally code added s.t.
1169 STDOUT/STDIN/STDERR will never be closed by Root::IO cleanup.
1171 o Bio::Tools::Genemark bug #1435 fixed which was missing last prediction
1173 o Bio::SeqIO::genbank
1174 - bug #1456 fixed which generated extra sequence lines
1175 - write moltype correctly for genpept
1177 1.2.1 Stable release update
1179 o Inclusion of WrapperBase, a needed component for StandAloneBlast
1181 o Addition from main trunk of Ontology objects, principly to allow
1182 BioSQL releases against 1.2.1
1184 o Fixes and cleanup of Bio::Coordinate modules
1186 o A fix to Bio::Index::EMBL allowing retrieval of entries using
1187 the primary accession number
1189 o Other bug fixes, including bpindex GenBank fix
1191 o Bio::SeqIO::genbank bug #1389 fixed
1193 1.2 Stable major release
1195 o More functionality added to Bio::Perl, the newbie module
1197 o Bug fixes in Bio::TreeIO::newick fixes bug introduced in 1.0.2
1198 Support for New Hampshire Extended (NHX) format parsing.
1200 o Bio::Tools added support for parsing Genomewise, Pseudowise, Est2Genome,
1201 Tmhmm, SignalP, Seg, RepeatMasker, FootPrinter, and a lightweight
1204 o New ontology parsing Bio::Ontology
1206 o Bug fixes in Bio::SearchIO for HMMer parsing, support for
1207 multi-report (mlib) fasta reports, support for waba and exonerate.
1209 o Bio::ClusterIO for parsing Unigene clusters
1211 o Bio::Assembly added for representing phrap and ace assembly clusters.
1213 o Rudimentary support for writing Chado XML (see
1214 GMOD project: www.gmod.org for more information)
1216 o Bio::Coordinate for mapping between different coordinate systems such
1217 as protein -> cDNA -> Exon -> DNA and back. Useful for mapping
1218 features into different coordinate systems.
1220 o Bio::DB::GenBank/Bio::DB::GenPept now support Entrez queries
1221 with the get_Stream_by_query method and supports the latest
1222 NCBI eutils interface.
1224 o Bugs fixed in Bio::SeqFeature::Collection an in-memory fast
1225 object for extracting subsets of features : currently only
1226 supports extraction by location.
1228 1.1.1 Developer release
1230 o Deprecated modules are now listed in the DEPRECATED file
1232 o New HowTo documents located in doc/howto describing
1233 a domain of Bioperl.
1235 o Note that bugs are now stored at redmine.open-bio.org/projects/bioperl/
1236 and all old bugs are searchable through the bugzilla interface.
1238 o Several reported bugs in Bio::Tools::Sigcleave and Bio::SimpleAlign
1239 have been addressed.
1241 o Support for Genewise parsing in Bio::Tools::Genewise
1243 o Start of Ontology framework with Bio::Ontology
1245 o Speedup to the Bio::Root::Root object method _rearrange.
1246 A global _load_module method was implemented to simplify the
1247 dynamic loading of modules ala Bio::SeqIO::genbank. This
1248 method is now used by all the XXIO (AlignIO,TreeIO,SearchIO,SeqIO,
1251 o Several performance improvements to sequence parsing in Bio::SeqIO.
1252 Attempt to speedup by reducing object creation overhead.
1254 o Bio::DB::GenBank and Bio::DB::GenPept use the NCBI's approved
1255 method for sequence retrieval with their E-utils CGI scripts.
1256 More work to support Entrez queries to their fullest is planned
1259 o Numerous fixes to Bio::SearchIO and sequence parsing (swissprot)
1261 1.1 Developer release
1263 o Bio::Tools::Run has been broken off into a new pkg bioperl-run,
1264 this separation removes some of the complexity in our test suite
1265 and separates the core modules in bioperl from those that need
1266 external programs to run.
1268 o With latest ExtUtils::MakeMaker module installed SGI/IRIX should
1269 not run into trouble running the makefile
1271 o Bio::Location and Bio::SeqIO::FTHelper are fixed to properly
1272 read,create,and write locations for grouped/split locations
1273 (like mRNA features on genomic sequence).
1275 o Bio::Tools::Phlyo added for wrappers for parsing Molphy (protml)
1276 and PAML (codeml,aaml, etc) parsing.
1278 o Bio::Tree:: objects expanded to handle testing monophyly,
1279 paraphyly, least common ancestor, etc.
1281 o Bio::Coordinate for mapping locations from different coordinate spaces
1283 o Bio::SearchIO::waba added for parsing WABA, Bio::SearchIO::hmmer
1284 added for parsing hmmpfam and hmmsearch output.
1286 o Bio::SearchIO::Writer::TextResultWriter for outputting
1287 a pseudo-blast textfile format
1290 1.0.2 Bug fix release
1292 o Note: The modules Bio::DB::GenBank and Bio::DB::GenPept provided
1293 in this release will not work after December 2002 when NCBI
1294 shuts off the old Entrez cgi scripts. We have already fixed
1295 on our main development branch and the functionality will be
1296 available in the next stable bioperl release (1.2) slated for
1299 o Numerous parsing bugs in Bio::SearchIO::fasta found through
1300 testset by Robin Emig. These were fixed as was the get_aln
1301 method in Bio::Search::HSP::GenericHSP to handle the extra
1302 context sequence that is provided with a FastA alignment.
1304 o Migrating differences between Bio::Search::XX::BlastXX to
1305 Bio::Search::XX::GenericXX objects. This included mechanism
1306 to retrieve whole list of HSPs from Hits and whole list of Hits from
1307 Results in addition to the current next_XX iterator methods that
1308 are available. Added seq_inds() method to GenericHSP which identifies
1309 indexes in the query or hit sequences where conserved,identical,gaps,
1310 or mismatch residues are located (adapted from Steve Chervitz's
1311 implementation in BlastHSP).
1313 o Bio::DB::GFF bugs fixed and are necessary for latest GBrowse release.
1314 Bio::DB::GFF::RelSegment is now Bio::SeqI compliant.
1316 o Bio::Graphics glyph set improved and extended for GBrowse release
1318 o Bio::Tree::Tree get_nodes implementation improvement thanks
1319 to Howard Ross notice performance problem when writing out
1322 o Bio::Location::Fuzzy::new named parameter -loc_type became
1323 -location_type, Bio::Location::Simple::new named parameter
1324 -seqid becamse -seq_id.
1326 o Fixed major Bio::AlignIO::emboss parsing bug on needle output,
1327 was mis-detecting that gaps should be placed at the beginning of
1328 the alignment when the best alignment starts internally in the
1331 1.0.1 Bug fix release
1333 o Minor bug fixes to Bio::DB:GFF. Glyph sets improved.
1335 o Parser fixes in SearchIO blast, fasta for more complete WU BLAST
1336 and mixed (3.3 - 3.4) versions of FASTA.
1338 o Small API change to add methods for completeness across
1339 implementations of Bio::Search objects. These new methods
1340 in the interface are implemented by the GenericXX object as well
1341 as the BlastXX objects.
1342 * Bio::Search::Result::ResultI
1343 - hits() method returns list of all Hits (next_hit is an
1346 * Bio::Search::Hit::HitI
1347 - hsps() method returns list of all HSPs (next_hsp is an
1350 o The Bio::SearchIO::Writer classes have been fixed to handle results
1351 created from either psiblast (Search::BlastXX objects) or
1352 blast|fasta|blastxml objects (Search::GenericXX objects). More work
1353 has to be done here to make it work properly and will nee major
1356 o Bugs in Bio::Tools::HMMER fixed, including
1357 * #1178 - Root::IO destructor wasn't being called
1358 * #1034 - filter_on_cutoff now behaves properly
1360 o Bio::SeqFeature::Computation initialization args fixed and
1363 o Tests are somewhat cleaner, flat.t now properly cleans up after itsself,
1365 o Updated FAQ with more example based answers to typical questions
1367 o Bug #1202 was fixed which would improperly join together qual values
1368 parsed by Bio::SeqIO::qual when a trailing space was not present before
1371 1.0.0 Major Stable Release
1373 This represents a major release of bioperl with significant
1374 improvements over the 0.7.x series of releases.
1376 o Bio::Tools::Blast is officially deprecated. Please see
1377 Bio::SearchIO for BLAST and FastA parsing.
1379 o The methods trunc() and subseq() in Bio::PrimarySeqI now accepts
1380 Bio::LocationI objects as well as start/end.
1382 o Bio::Biblio contains modules for Bibliographic data.
1383 Bio::DB::Biblio contains the query modules. Additionally one can
1384 parse medlinexml from the ebi bibliographic query service (BQS)
1385 system and Pubmed xml from NCBI. See Martin Senger's
1386 documentation in Bio::Biblio for more information.
1388 o Bio::DB::Registry is a sequence database registry part of
1389 Open Bioinformatics Database Access. See
1390 http://obda.open-bio.org for more information.
1392 o File-based and In-Memory Sequence caching is provided by
1393 Bio::DB::InMemoryCache and Bio::DB::FileCache which acts like a
1396 o Bio::Graphics for rendering sequences as PNG,JPG, or GIFs has
1397 been added by Lincoln Stein.
1399 o XEMBL SOAP service access in provided in Bio::DB::XEMBL.
1401 o A FAQ has been started and is included in the release to provide
1402 a starting point for frequent questions and issues.
1404 0.9.3 Developer's release
1406 o Event based parsing system improved (SearchIO). With parsers for
1407 XML Blast (blastxml), Text Blast (blast), and FASTA results (fasta).
1408 Additionally a lazy parsing system for text and html blast reports was
1409 added and is called psiblast (name subject to change in future releases).
1411 o Bio::Search objects improved and standardized with associated Interfaces
1412 written. The concept of a search "Hit" was standardized to be called
1413 "hit" consistently and the use of "subject" was deprecated in all active
1416 o Bio::Structure added (since 0.9.1) for Protein structure objects
1417 and PDB parser to retrieve and write these structures from data files.
1419 o Several important Bio::DB::GFF bug fixes for handling features that
1420 are mapped to multiple reference points. Updated mysql adaptor
1421 so as to be able to store large (>100 megabase) chunks of DNA into
1422 Bio::DB::GFF databases.
1424 0.9.2 Developer's release
1426 o Bio::Search and Bio::SearchIO system introduced for event based
1427 parsing of Blast,Fasta reports Bio::SearchIO supports ncbi BLAST
1428 in text and XML and FASTA reports in standard output format.
1430 o Bio::Tree and Bio::TreeIO for phylogenetic trees. A Random tree
1431 generator is included in Bio::TreeIO::RandomTrees and a
1432 statistics module for evaluating.
1434 o Bio::DB::GFF, Lincoln Stein's GFF database suitable as a DB
1435 server for DAS servers.
1437 o Bio::Tools::BPlite is provides more robust parsing of BLAST
1438 files. The entire BPlite system migrated to using Bio::Root::IO
1439 for the data stream.
1441 o Bio::Tools::Alignment for Consed and sequence Trimming
1444 o Bio::Structure for Protein structure information and parsing
1446 o Bio::DB::GenBank/Bio::DB::GenPept updated to new NCBI Entrez
1447 cgi-bin entry point which should be more reliable.
1449 o Bio::Map and Bio::MapIO for biological map navigation and a
1450 framework afor parsing them in. Only preliminary work here.
1452 o Interface for executing EMBOSS programs locally in Bio::Factory::EMBOSS
1453 Future work will integrate Pise and allow submission of analysis on
1456 o Bio::AnnotationCollectionI and Bio::Annotation::Collection
1457 introduced as new objects for handling Sequence Annotation
1458 information (dblinks, references, etc) and is more robust that
1461 o Bio::Tools::FASTAParser introduced.
1463 o Scripts from the bioperl script submission project and new
1464 scripts from bioperl authors are included in "scripts" directory.
1466 o Factory objects and interfaces are being introduced and are more
1469 o Bio::Root::Root introduced as the base object while
1470 Bio::Root::RootI is now simply an interface.
1472 o Bio::DB::RefSeq provides database access to copy of the NCBI
1473 RefSeq database using the EBI dbfetch script.
1475 0.9.0 Developer's release
1477 o perl version at least 5.005 is now required instead of perl 5.004
1479 o Bio::Tools::Run::RemoteBlast is available for running remote
1482 o Bio::Tools::BPbl2seq was fixed to handle multiple HSPs.
1484 o Bio::SeqFeature::GeneStructure migrated to Bio::SeqFeature::Gene.
1485 Also added are related modules UTR3, UTR5, Exon, Intron,
1486 Promotor, PolyA and Transcript.
1488 o Speedup of translate method in PrimarySeq
1490 o Bio::SimpleAlign has new methods: location_from_column(), slice(),
1491 select(), dot(), get_seq_by_pos(), column_from_residue_number()
1493 o Various fixes to Variation toolkit
1495 o Bio::DB::EMBL provides database access to EMBL sequence data.
1496 Bio::DB::Universal provides a central way to point to indexes
1497 and dbs in a single interface.
1499 o Bio::DB::GFF - a database suitable for running DAS servers locally.
1501 o Bio::Factory::EMBOSS is still in design phase as is
1502 Bio::Factory::ApplicationFactoryI
1504 o Dia models for bioperl design are provided in the models/ directory
1506 0.7.2 Bug fix release
1508 o documentation fixes in many modules - SYNOPSIS code verified
1509 to be runnable in many (but not all modules)
1511 o corrected MANIFEST file from 0.7.1 release
1513 o Bug fix in Bio::SeqIO::FTHelper to properly handle
1516 o Bio::SeqIO::genbank
1517 * Correct parsing and writing of genbank format with protein data
1518 * moltype and molecule separation
1520 o Bio::SeqIO::largefasta fix to avoid inifinite loops
1522 o Bio::SimpleAlign fixed to correctly handle consensus
1523 sequence calculation
1525 o Bio::Tools::HMMER supports hmmer 2.2g
1527 o Bio::Tools::BPlite to support report type specific parsing. Most
1528 major changes are not on the 0.7 branch.
1530 o Bio::Tools::Run::StandAloneBlast exists_blast() fixed and works
1533 o Bio::Variation::AAChange/RNAChange corrected labels and mutated alleles
1534 in several types of mutations:
1535 1.) AA level: deletion, complex
1536 2.) AA level: complex, inframe
1537 3.) RNA level: silent
1539 o BPbl2seq parsing of empty reports will not die, but will return
1540 a valid, empty, Bio::SeqFeature::SimilarityFeature for
1541 $report->query() and $report->subject() methods. So an easy
1542 way to test if report was empty is to see if
1543 $report->query->seqname is undefined.
1545 0.7.1 Bug fix release
1547 o Better parsing of genbank/EMBL files especially fixing bugs
1548 related to Feature table parsing and locations on remote
1549 sequences. Additionally, species name parsing was better.
1551 o Bio::SeqIO::genbank can parse now NCBI produced genbank database
1552 which include a number of header lines.
1554 o More strict genbank and EMBL format writing (corrected number of
1555 spaces where appropriate).
1557 o Bio::Tools::BPlite can better parse BLASTX reports - see BUGS
1558 for related BPlite BUGS that are unresolved in this release.
1560 o Bio::DB::GenBank, Bio::DB::GenPept have less problems
1561 downloading sequences from NCBI via HTTP. Bio::DB::SwissProt can
1562 use expasy mirrors or EBI dbfetch cgi-script.
1564 o A moderate number of documentation improvements were made as
1565 well to provide a better code synopsis in each module.
1568 0.7 Large number of changes, including refactoring of the
1569 Object system, new parsers, new functionality and
1570 all round better system. Highlights are:
1573 o Refactored root of inheritance: moved to a lightweight Bio::Root::RootI;
1574 Bio::Root::IO for I/O and file/handle capabilities.
1576 o Imported BPlite modules from Ian Korf for BLAST
1577 parsing. This is considered the supported BLAST parser;
1578 Bio::Tools::Blast.pm will eventually phase out due to lack of support.
1580 o Improved Sequence Feature model. Added complete location
1581 modelling (with fuzzy and compound locations). See
1582 Bio::LocationI and the modules under Bio/Location. Added
1583 support in Genbank/EMBL format parsing to completely parse
1584 feature tables for complex locations.
1586 o Moved special support for databanks etc to specialized modules under
1587 Bio/Seq/. One of these supports very large sequences through
1588 a temporary file as a backend.
1590 o Explicit Gene, Transcript and Exon SeqFeature objects, supporting
1591 CDS retrieval and exon shuffling.
1593 o More parsers: Sim4, Genscan, MZEF, ESTScan, BPbl2seq, GFF
1595 o Refactored Bio/DB/GenBank+GenPept. There is now also DB/SwissProt and
1596 DB/GDB (the latter has platform-specific limitations).
1598 o New analysis parser framework for HT sequence annotation (see
1599 Bio::SeqAnalysisParserI and Bio::Factory::SeqAnalysisParserFactory)
1601 o New Alignment IO framework
1603 o New Index modules (Swissprot)
1605 o New modules for running Blast within perl
1606 (Bio::Tools::Run::StandAloneBlast). Added modules for running
1607 Multiple Sequence Alignment tools ClustalW and TCoffee
1608 (Bio::Tools::Run::Alignment).
1610 o New Cookbook-style tutorial (see bptutorial.pl). Improved
1611 documentation across the package.
1613 o Much improved cross platform support. Many known incompatibilities
1614 have been fixed; however, NT and Mac do not work across the entire
1615 setup (see PLATFORMS).
1617 o Many bug fixes, code restructuring, etc. Overall stability and
1618 maintainability benefit a lot.
1620 o A total of 957 automatic tests
1625 There are very few functionality changes but a large
1626 number of software improvements/bug fixes across the package.
1628 o The EMBL/GenBank parsing are improved.
1630 o The Swissprot reading is improved. Swissprot writing
1631 is disabled as it doesn't work at all. This needs to
1632 wait for 0.7 release
1634 o BLAST reports with no hits are correctly parsed.
1636 o Several other bugs of the BLAST parser (regular expressions, ...)
1639 o Old syntax calls have been replaced with more modern syntax
1641 o Modules that did not work at all, in particular the Sim4
1642 set have been removed
1644 o Bio::SeqFeature::Generic and Bio::SeqFeature::FeaturePair
1645 have improved compliance with interface specs and documentation
1647 o Mailing list documentation updated throughout the distribution
1649 o Most minor bug fixes have happened.
1651 o The scripts in /examples now work and have the modern syntax
1652 rather than the deprecated syntax
1655 0.6.1 Sun April 2 2000
1657 o Sequences can have Sequence Features attached to them
1658 - The sequence features can be read from or written to
1659 EMBL and GenBank style flat files
1661 o Objects for Annotation, including References (but not
1662 full medline abstracts), Database links and Comments are
1665 o A Species object to represent nodes on a taxonomy tree
1668 o The ability to parse HMMER and Sim4 output has been added
1670 o The Blast parsing has been improved, with better PSI-BLAST
1671 support and better overall behaviour.
1673 o Flat file indexed databases provide both random access
1674 and sequential access to their component sequences.
1676 o A CodonTable object has been written with all known
1677 CodonTables accessible.
1679 o A number of new lightweight analysis tools have been
1680 added, such as molecular weight determination.
1682 The 0.6 release also has improved software engineering
1684 o The sequence objects have been rewritten, providing more
1685 maintainable and easier to implement objects. These
1686 objects are backwardly compatible with the 0.05.1 objects
1688 o Many objects are defined in terms of interfaces and then
1689 a Perl implementation has been provided. The interfaces
1690 are found in the 'I' files (module names ending in 'I').
1692 This means that it is possible to wrap C/CORBA/SQL access
1693 as true "bioperl" objects, compatible with the rest of
1696 o The SeqIO system has been overhauled to provide better
1697 processing and perl-like automatic interpretation of <>
1700 o Many more tests have been added (a total of 172 automatic
1701 tests are now run before release).
1705 0.05.1 Tue Jun 29 05:30:44 1999
1706 - Central distribution now requires Perl 5.004. This was
1707 done to get around 5.003-based problems in Bio/Index/*
1709 - Various bug fixes in the Bio::Tools::Blast modules
1710 including better exception handling and PSI-Blast
1711 support. See Bio/Tools/Blast/CHANGES for more.
1712 - Fixed the Parse mechanism in Seq.pm to use readseq.
1713 Follow the instructions in README for how to install
1714 it (basically, you have to edit Parse.pm).
1715 - Improved documentation of Seq.pm, indicating where
1716 objects are returned and where strings are returned.
1717 - Fixed uninitialized warnings in Bio::Root::Object.pm
1718 and Bio::Tools::SeqPattern.pm.
1719 - Bug fixes for PR#s: 30,31,33-35,41,42,44,45,47-50,52.
1721 0.05 Sun Apr 25 01:14:11 1999
1722 - Bio::Tools::Blast modules have less memory problems
1723 and faster parsing. Webblast uses LWP and supports
1724 more functionality. See Bio/Tools/Blast/CHANGES for more.
1725 - The Bio::SeqIO system has been started, moving the
1726 sequence reformatting code out of the sequence object
1727 - The Bio::Index:: system has been started, providing
1728 generic index capabilities and specifically works for
1729 Fasta formatted databases and EMBL .dat formatted
1731 - The Bio::DB:: system started, providing access to
1732 databases, both via flat file + index (see above) and
1734 - The scripts/ directory, where industrial strength scripts
1735 are put has been started.
1736 - Many changes - a better distribution all round.
1738 0.04.4 Wed Feb 17 02:20:13 1999
1739 - Bug fixes in the Bio::Tools::Blast modules and postclient.pl
1740 (see Bio::Tools::Blast::CHANGES).
1741 - Fixed a bug in Bio::Tools::Fasta::num_seqs().
1742 - Beefed up the t/Fasta.t test script.
1743 - Small fix in Bio::Seq::type() (now always returns a string).
1744 - Changed Bio::Root::Utilities::get_newline_char() to
1745 get_newline() since it could return more than one char.
1746 - Added $NEWLINE and $TIMEOUT_SECS to Bio::Root::Global.
1747 - Changed default timeout to 20 seconds (was 3).
1748 - Moved lengthy modification notes to the bottom of some files.
1749 - Fixed SimpleAlign write_fasta bug.
1750 - Beefed up SimpleAlign.t test
1752 0.04.3 Thu Feb 4 07:48:53 1999
1753 - Bio::Root::Object.pm and Global.pm now detect when
1754 script is run as a CGI and suppress output that is only
1755 appropriate when running interactively.
1756 - Bio::Root::Err::_set_context() adds name of script ($0).
1757 - Added comments in Bio::Tools::WWW.pm and Bio::Root::Utilities.pm
1758 regarding the use of the static objects via the qw(:obj) tag.
1759 - Fixed the ambiguous reverse calls in Seq.pm and UnivAln.pm to
1760 CORE::reverse, avoiding Perl warnings.
1761 - Bug fixes in Bio::Tools::Blast modules (version 0.074) and
1762 example scripts (see Bio::Tools::Blast::CHANGES).
1763 - examples/seq/seqtools.pl no longer always warns about using
1764 -prot or -nucl command-line arguments; only when using the
1766 - Methods added to Bio::Root::Utilities: create_filehandle(),
1767 get_newline_char(), and taste_file() to generalize filehandle
1768 creation and autodetect newline characters in files/streams
1769 (see bug report #19).
1770 - Bio::Root::IOManager::read() now handles timeouts and uses
1771 Utilities::create_filehandle().
1772 - Bio::Tools::Fasta.pm uses Utilities::get_newline_char() instead
1773 of hardwiring in "\n".
1774 - Bug fixes in the Bio::SimpleAlign and Bio::Tools::pSW
1776 0.04.2 Wed Dec 30 02:27:36 1998
1777 - Bug fixes in Bio::Tools::Blast modules, version 0.073
1778 (see Bio::Tools::Blast::CHANGES).
1779 - Changed reverse calls in Bio/Seq.pm and Bio/UnivAln.pm
1780 to CORE::reverse (prevents ambiguous warnings with 5.005).
1781 - Appending '.tmp.bioperl' to temporary files created by
1782 Bio::Root::Utilities::compress() or uncompress() to
1783 make it easy to identify & cleanup these files as needed.
1784 - Developers: Created CVS branch release-0-04-bug from
1785 release-0-04-1. Before making bug fixes to the 0.04.1 release,
1786 be sure to cvs checkout this branch into a clean area.
1788 0.04.1 Wed Dec 16 05:39:15 1998
1789 - Bug fixes in Bio::Tools::Blast modules, version 0.072
1790 (see Bio::Tools::Blast::CHANGES).
1791 - Compile/SW/Makefile.PL now removes *.o and *.a files
1794 0.04 Tue Dec 8 07:49:19 1998
1795 - Lots of new modules added including:
1796 * Ewan Birney's Bio::SimpleAlign.pm, Bio::Tools::AlignFactory.pm,
1797 and Bio/Compile directory containing XS-linked C code for
1798 creating Smith-Waterman sequence alignments from within Perl.
1799 * Steve Chervitz's Blast distribution has been incorporated.
1800 * Georg Fuellen's Bio::UnivAln.pm for multiple alignment objects.
1801 - Bio/examples directory for demo scripts for all included modules.
1802 - Bio/t directory containing test suit for all included modules.
1803 - For changes specific to the Blast-related modules prior to
1804 incorporation in this central distribution, see the CHANGES
1805 file in the Bio/Tools/Blast directory.
1807 0.01 Tue Sep 8 14:23:22 1998
1808 - original version from central CVS tree; created by h2xs 1.18