1 ---------------------------------------------------------
2 Revision history for BioPerl core modules
3 ---------------------------------------------------------
4 The comprehensive history and ongoing development of BioPerl:
6 http://github.com/bioperl/bioperl-live
8 Some of that history is also highlighted on our wiki:
10 http://www.bioperl.org/wiki/Change_log
11 http://www.bioperl.org/wiki/History_of_BioPerl
13 Bugs and requested features list:
15 https://redmine.open-bio.org/projects/bioperl
17 CPAN releases are branched from 'master'.
18 ---------------------------------------------------------
22 * Minor update to address CPAN test failures
26 * Remove Bio::Biblio and related files [carandraug]
27 - this cause version clashes with an independently-released
28 version of Bio::Biblio
34 * Hash randomization fixes for perl 5.18.x
35 - Note: at least one module (Bio::Map::Physical) still has a failing test;
36 this is documented in bug #3446 and has been TODO'd; we will be pulling
37 Bio::Map and similar modules out of core into separate distributions in the
38 1.7.x release series [cjfields]
42 * Bio::Seq::SimulatedRead
43 - New module to represent reads taken from other sequences [fangly]
45 - New regexp() method to create regular expressions from IUPAC sequences
47 * Bio::SeqFeature::Primer and Bio::Seq::PrimedSeq:
48 - Code refresh [fangly]
50 - Added support for the Greengenes and Silva taxonomies [fangly]
51 * Bio::Tree::TreeFunctionsI
52 - get_lineage_string() represents a lineage as a string [fangly]
53 - add_trait() returns instead of reporting an error when the column
54 number is exceeded in add_trait() [fangly]
55 - Option to support tree leaves without trait [fangly]
56 - Allow ID of 0 in trait files [fangly]
57 * Bio::DB::Taxonomy::list
58 - Misc optimizations [fangly]
59 - Option -names of get_taxon() to help with ambiguous taxa [fangly]
60 * Bio::DB::Taxonomy::*
61 - get_num_taxa() returns the number of taxa in the database [fangly]
62 * Bio::DB::Fasta and Bio::DB::Qual
63 - support indexing an arbitrary list of files [fangly]
64 - user can supply an arbitrary index file name [fangly]
65 - new option to remove index file at the end [fangly]
67 - now handles IUPAC degenerate residues [fangly]
68 * Bio::PrimarySeq and Bio::PrimarySeqI
69 - speed improvements for large sequences [Ben Woodcroft, fangly]
71 - tightened and optimized quality string validation [fangly]
73 - new method and option 'block', to create FASTA output with space
74 intervaled blocks (similar to genbank or EMBL) has been implemented.
75 - package variables $WIDTH and $DEFAULT_SEQ_ID_TYPE have been removed
76 in favour of the methods 'width' and 'preferred_id_type` respectively.
78 - moved from bioperl-live into the separate distribution Bio-FeatureIO
79 * Bio::SeqFeature::Annotated
80 - moved from bioperl-live into the separate distribution Bio-FeatureIO
81 * Bio::Cluster::SequenceFamily
82 - improved performance when using get_members with overlapping multiple
84 * Bio::SearchIO::hmmer3
85 - now supports nhmmer [bosborne]
89 * [3302] Fixes bug in Bio::SearchIO::hmmer2.pm to correctly parse
90 multi-query hmmer output [Francisco J. Ossandon, Paul Cantalupo]
91 * [3421] Fixes bug in Bio::SearchIO::hmmer2.pm to correctly parse an HSP
92 with a line full of dashes [Francisco J. Ossandon, Paul Cantalupo]
93 * [3298] Fix bug in Bio::SearchIO::blast.pm where algorithm version
94 information was lost in a multi-result blast file [Paul Cantalupo]
95 * [3343] Fix bug in Bio::SearchIO::blasttable.pm to correctly calculate
96 total gaps [Paul Cantalupo]
97 * [3375] Fix DBLINK parsing bug in Bio::SeqIO::genbank.pm [Paul Cantalupo]
98 * [3376] Fix bug in Bio::SearchIO::hmmer2.pm to correctly handle case
99 when end of domain indicator is split across lines [Paul Cantalupo]
100 * [3240] Bio::AlignIO::stockholm now parses simple sequences [Bernd Web,
102 * [3237] Bio::DB::Fasta now allows blank lines between sequences, catches
103 instances where blank lines are within sequences [cjfields]
104 * Bio::DB::Fasta reports correct alphabet for files with multiple sequence
106 * Bio::DB::Fasta rev-comps sequences other than DNA properly [fangly]
107 * [3238] Fixes for Bio::DB::SeqFeature::Store::DBI::Pg [Thomas Burkhard,
109 * Various fixes for Stockholm file indexing and processing [bosborne]
110 * Fix edge case in FASTQ parsing where sequence of length 1 and qual of 0
111 breaks parsing [cjfields]
112 * Fix case where Bio::Seq::Meta* objects with no meta information could not
113 be reverse-complemented [fangly]
114 * Fix bug for fields without aliases in Bio::DB::Query::HIVQuery [fangly]
115 * Fix Bio::PopGen::IO::phase: sort values lexically instead of numerically
116 when unsure that values will be numerical [fangly]
117 * Fix undef warnings in Bio::SeqIO::embl [fangly]
118 * Fix undef warnings in Bio::DB::Fasta and Bio::DB::Qual [fangly]
119 * Fix Bio::Tools::IUPAC should accept any sequence object [fangly]
120 * Fix for 'Inappropriate ioctl' in Bio::DB::Store::berkeleydb3 [Olivier
122 * Bio::SeqFeature::Generic SeqfeatureI compliance: methods primary_tag,
123 source_tag and display_name must return a string, not undef [fangly]
124 * Bio::SimpleAlign and Bio::Seq compliance with Bio::FeatureHolderI
125 add_SeqFeature takes a single argument [fangly]
126 * Use cross-platform filenames and temporary directory in
127 Bio::DB::Taxonomy::flatfile [fangly]
128 * Fix bug in Bio::DB::Taxonomy::list where taxa with no ancestors were not
129 properly identified as existing taxa in the database [fangly]
130 * Fix issue where a Bio::DB::Taxonomy::list object could not be created
131 without also passing a lineage to store [fangly]
132 * Prevent passing a directory to the gi2taxid option (-g) of
133 bp_classify_hits_kingdom.pl and remove an 'earlier declaration' warning
135 * Fixed bp_genbank2gff3.pl crash when missing source feature date [fangly]
136 * Bio::PrimarySeq constructor -direct works for -seq or -ref_to_seq [fangly]
137 * Bio::Cluster::SequenceFamily - checks if the sequence has a Bio::Species
138 object before trying to access, and no longer returns repeated sequences.
145 * Use of AcePerl is deprecated; Ace.pm isn't actively maintained, and
146 modules using Ace will also be deprecated [lds, cjfields]
147 * Minor bug fix release
148 * Bio::SeqIO::gbxml tests require XML::SAX [hartzell]
149 * Address Build.PL issues when DBI is not present [hartzell]
150 * Skip gbxml.t and Interpro tests when modules not installed [cjfields]
151 * Remove deprecated code for perl 5.14.0 compat [cjfields]
152 * Due to schema changes and lack of support for older versions, support
153 for NeXML 0.9 is only (very) partially implemented.
154 See: https://redmine.open-bio.org/issues/3207
158 * [3205] - small fix to Bio::Perl blast_sequence() to make compliant with
159 docs [genehack, cjfields]
160 * $VERSION for CPAN/cpanm-based installs was broken; force setting of
161 module version from dist_version (probably not the best way to do this,
162 but it seems to work) [rbuels, cjfields]
165 1.6.900 April 14, 201
169 * This will probably be the last release to add significant features to
170 core modules; subsequent releases will be for bug fixes alone.
171 We are planning on a restructuring of core for summer 2011, potentially
172 as part of the Google Summer of Code. This may become BioPerl 2.0.
173 * Version bump represents 'just prior to v 1.7'. We may have point
174 releases to deal with bugs, with increments of 1.6.901, 1.6.902, etc.
175 This code essentially is what is on the github master branch.
179 * Core code updated for perl 5.12.x [cjfields, Charle Tilford]
181 - major overhaul of Bio::Tree code by Greg Jordan, fixes several bugs
182 - removal of Scalar::Util::weaken code, which was causing odd headaches
183 with premature GC, memory leaks with perl 5.10.0, etc [cjfields]
184 * Bio::DB::SeqFeature bug fixes for GBrowse2 compatibility [lds, scottcain,
186 * Bio::SeqIO::msout, Bio::SeqIO::mbsout - parsers for ms and mbs
189 - bug 2515 - new contribution [Ryan Golhar, jhannah]
191 - support for reading Maq, Sam and Bowtie files [maj]
192 - support for reading 454 GS Assembler (Newbler) ACE files [fangly]
193 - bug 2483: support for writing ACE files [Joshua Udall, fangly]
194 - bug 2599: support DBLINK annotation in GenBank files [cjfields]
195 - bug 2726: reading/writing granularity: whole scaffold or one contig
196 at a time [Joshua Udall, fangly]
198 - Added parsing of xrefs to OBO files, which are stored as secondary
199 dbxrefs of the cvterm [Naama Menda]
200 - General Interpro-related code refactors [dukeleto, rbuels, cjfields]
201 * PAML code updated to work with PAML 4.4d [DaveMessina]
205 * [3198] - sort tabular BLAST hits by score [DaveMessina]
206 * [3196] - fix invalid metadata produced by latest Module::Build [cjfields]
207 * [3190] - RemoteBlast GAPCOSTS regex fix [Ali Walsh, cjfields]
208 * [3185] - Bio::Tools::SeqStats->get_mol_wt now gives correct MW
210 * [3178] - fix tr/// issue in Bio::Range [Andrew Conley, cjfields]
211 * [3172] - Bio::DB::Fasta - catch possibly bad FASTA files [cjfields]
212 * [3164] - TreeFunctionsI syntax bug [gjuggler]
213 * [3163] - AssemblyIO speedup [fangly]
214 * [3160] - Bio::SearchIO::Writer::TextResultWriter output [Paul Cantalupo,
216 * [3159] - add SwissPfam support to bp_index.PLS [hyphaltip]
217 * [3158] - fix EMBL file mis-parsing [cjfields]
218 * [3157] - Bio::Restriction::Analysis 'sizes' method fixed [Marc Perry,
220 * [3153] - fix SeqIO::swiss TagTree issues [Charles Tilford, cjfields]
221 * [3148] - URL change for UniProt [cjfields]
222 * [3145] - AXT off-by-1 error [Aaron Goodman, cjfields]
223 * [3136] - HMMer3 parser fixes [kblin]
224 * [3126] - catch description [Toshihiko Akiba]
225 * [3122] - Catch instances where non-seekable filehandles were being
226 seek'd w/o checking for status [Stefan Kirov, Roy Chaudhuri]
227 * [3121] - Bio::OntologyIO cannot parse the full InterPro XML file
228 [dukeleto, rbuels, cjfields]
229 * [3120] - bp_seqfeature_gff3.pl round-trip fixes [genehack, David Breimann,
231 * [3116,3117] - perl 5.12.x warnings fixed [cjfields, Charles Tilford]
232 * [3110] - Better 'namespace' support for bp_seqfeature_load.PLS [dbolser,
234 * [3107] - BLAST alignment column_from_residue_number() [cjfields]
235 * [3104] - Bio::Species single node hierarchies [Charles Tilford, cjfields]
236 * [3092, 3090] - parsing of BLAST HSP stats [Razi Khaja, cjfields]
237 * [3089] - HSPTableWriter missing methods [Robson de Souza, cjfields]
238 * [3086] - EMBL misparsing long tags [kblin, cjfields]
239 * [3085] - CommandExts and array of files [maj, hyphaltip]
240 * [3077] - Bio::SimpleAlign slice() now correctly computes seq coordinates
241 for alignment slices [Ha X. Dang, cjfields]
242 * [3076] - XMFA alignment strand wrong [Ha X., cjfields]
243 * [3073] - fix parsing of GenBank files from RDP [cjfields]
244 * [3068] - FASTQ parse failure with trailing 0 [cjfields]
245 * [3064] - All-gap midline BLAST report issues [cjfields]
246 * [3063] - BLASt report RID [Razi Khaja, cjfields]
247 * [3058] - SearchIO::fasta parsing [DaveMessina, cjfields]
248 * [3053] - LOCUS line formatting [M. Wayne, cjfields]
249 * [3039] - correct Newick output root node branch length [gjuggler,
251 * [3038] - SELEX alignment error [Bernd, cjfields]
252 * [3033] - PrimarySeq ID setting [Bernd, maj]
253 * [3032] - Fgenesh errors [Wes Barris, hyphaltip]
254 * [3034] - AlignIO::clustal output [Bernd, DaveMessina]
255 * [3031] - Parse algorithm ref for BLAST [Razi Khaja, cjfields]
256 * [3028] - Bio::TreeIO::nexus and FigTree compat [Kevin Balbi, cjfields]
257 * [3025] - Bio::SeqIO::embl infinite loop [Adam Sjøgren, cjfields]
258 * [3040, 3023, 2974, 2921, 2753, 2636, 2482] - PAML parser fixed, works with
259 PAML 4.4d [DaveMessina]
260 * [3015, 3022] - Bio::Restriction withrefm regexp [Emmanuel Quevillon,
262 * [3020] - GFF3Loader alias attribute [Nathan Weeks, cjfields]
263 * [3018, 3019, 3021] - gmap_f9 parsing [Kiran Mukhyala, cjfields]
264 * [3017] - using threads with Bio::DB::GenBank [cjfields]
265 * [3012] - Bio::Root::HTTPget fixes [maj, cjfields]
266 * [3011] - namespace support for SF::Store::DBI::Pg [Adam Witney, cjfields]
267 * [3002] - Bio::DB::EUtilities NCBI policy updates [cjfields]
268 * [3001] - seq identifier '0' dropped with FASTA [Michael Kuhn, maj]
269 * [2984] - let LocatableSeq decide on length of phylip aln [Adam Witney,
271 * [2983] - fix score/percent ID mixup [Alexie Papanicolaou]
272 * [2977] - TreeIO issues [DaveMessina]
273 * [2959] - Bio::SeqUtils->revcom_with_features [Roy Chaudhuri, maj]
274 * [2944] - Bio::Tools::GFF score [cjfields]
275 * [2942] - correct MapTiling output [maj]
276 * [2939] - PDB residue insertion codes [John May, maj]
277 * [2930] - PrimarySeqI term symbol [Adam Sjøgren, maj]
278 * [2928] - GuessSeqFormat raw [maj]
279 * [2926] - Bio:Tools::TandemRepeatsFinder seq_id [takadonet, cjfields]
280 * [2922] - open() directive issue [cjfields]
281 * [2915] - GenBank parser infinite loop [Francisco Ossandon, cjfields]
282 * [2901] - DNAStatistics div by zero error [Janet Young, cjfields]
283 * [2899] - SeqFeature::Store host issues [lstein, dbolser]
284 * [2897] - Add a "mask_below_threshold" method to Seq::Quality [dbolser,
286 * [2881] - .scf files don't' roundtrip [Adam Sjøgren, cjfields]
287 * [2876] - CDD search with RemoteBlast [Malcolm Cook]
288 * [2863] - Root::IO::_initialize_io causes crash [rbuels, maj, DaveMessina]
289 * [2845] - Bio::Seq::Quality gives seq with no ID [Tristan Lefebure, cjfields]
290 * [2843] - FeatureIO BED to GFF fails w/ no phase [cassjm cjfields]
291 * [2773] - Bio::Tree::Node premature GC [Morgan Price, cjfields]
292 * [2764] - add ID Tracker helper for SwissProt [heikki, cjfields]
293 * [2758] - Bio::AssemblyIO ace problems [fangly]
294 * [2744] - Bio::LocatableSeq::end [Bernd, cjfields]
295 * [2726] - ace file IO [Josh, fangly]
296 * [2700] - Refactor Build.PL [cjfields]
297 * [2673] - addition of simple Root-based clone() method [cjfields]
298 * [2648] - Bio::Assembly::Scaffold->get_all_seq_ids [dbolser, fangly]
299 * [2599] - support for DBLINK annotation in GenBank files [cjfields]
300 * [2594] - Bio::Species memory leak [cjfields]
301 * [2515] - GenBank XML parser [jhannah]
302 * [2499] - Method "pi" in package Bio::PopGen::Statistics [hyphaltip]
303 * [2483] - Bio::Assembly::IO::ace write_assembly implemented [fangly]
304 * [2350] - ID consistency btwn Bio::SeqI, Bio::Align::AlignI [fangly,
306 * [1572] - no docs Bio::Location::Simple/Atomic::trunc [hyphaltip]
310 * Bio::Expression modules - these were originally designed to go with the
311 bioperl-microarray suite of tools, however they have never been completed
312 and so have been removed from the distribution. The original code has
313 been moved into the inactive bioperl-microarray suite. [cjfields]
317 * Repository moved from Subversion (SVN) to
318 http://github.com/bioperl/bioperl-live [cjfields]
319 * Bug database has moved to Redmine (https://redmine.open-bio.org)
320 * Bio::Micrarray - the tools developed for ReSeq chip analysis by Marian
321 Thieme have been moved to their own distribution (Bio-Microarray).
324 1.6.1 Sept. 29, 2009 (point release)
325 * No change from last alpha except VERSION and doc updates [cjfields]
327 1.6.0_6 Sept. 27, 2009 (sixth 1.6.1 alpha)
328 * Fix for silent OBDA bug related to FASTA validation [cjfields]
330 1.6.0_5 Sept. 27, 2009 (fifth 1.6.1 alpha)
331 * Possible fix for RT 49950 (Strawberry Perl installation) [cjfields]
332 * [RT 50048] - removed redundant VERSION, which was borking CPANPLUS
334 * BioPerl.pod -> BioPerl.pm (Perl Best Practices) [cjfields]
336 1.6.0_4 Sept. 25, 2009 (fourth 1.6.1 alpha)
337 * WinXP test fixes [cjfields, maj]
338 * BioPerl.pod added for descriptive information, fixes CPAN indexing
340 * Minor doc fixes [cjfields]
342 1.6.0_3 Sept. 22, 2009 (third 1.6.1 alpha)
343 * Fix tests failing due to merging issues [cjfields]
344 * More documentation updates for POD parsing [cjfields]
346 1.6.0_2 Sept. 22, 2009 (second 1.6.1 alpha)
348 - fix YAML meta data generation [cjfields]
350 1.6.0_1 Sept. 15, 2009 (first 1.6.1 alpha)
351 * Bio::Align::DNAStatistics
352 - fix divide by zero problem [jason]
354 - bug 2813 - fix faulty logic to detect end-of-stream [cjfields]
355 * Bio::AlignIO::stockholm
356 - bug 2796 - fix faulty logic to detect end-of-stream [cjfields]
357 * Bio::Assembly::Tools::ContigSpectrum
358 - function to score contig spectrum [fangly]
359 * Bio::DB::EUtilities
360 - small updates [cjfields]
362 - berkeleydb database now autoindexes wig files and locks correctly
365 - various small updates for stability; tracking changes to LANL
366 database interface [maj]
367 * Bio::DB::SeqFeature (lots of updates and changes)
368 - add Pg, SQLite, and faster BerkeleyDB implementations [lstein, scain]
369 - bug 2835 - patch [Dan Bolser]
370 - bug RT 44535 - patch FeatureFileLoader [Cathy Gresham]
372 - bug 2764 - idtracker() method [cjfields, courtesy Neil Saunders]
373 * Bio::Factory::FTLocationFactory
374 - mailing list bug fix [cjfields]
376 - performance work on column_from_residue_number [hartzell]
377 * Bio::Matrix::IO::phylip
378 - bug 2800 - patch to fix phylip parsing [Wei Zou]
380 - Google Summer of Code project from Chase Miller - parsers for Nexml
381 file format [maj, chmille4]
383 - Make Individual, Population, Marker objects AnnotatableI [maj]
384 - simplify LD code [jason]
386 - deal with empty intersection [jason]
388 - significant overhaul of Bio::Restriction system: complete support for
389 external and non-palindromic cutters. [maj]
391 - CPANPLUS support, no automatic installation [sendu]
393 - allow IO::String (regression fix) [cjfields]
394 - catch unintentional undef values [cjfields]
395 - throw if non-fh is passed to -fh [maj]
396 * Bio::Root::Root/RootI
397 - small debugging and core fixes [cjfields]
399 - bug RT 48813 - fix for Strawberry Perl bug [kmx]
400 * Bio::Root::Utilities
401 - bug 2737 - better warnings [cjfields]
403 - tiling completely refactored, HOWTO added [maj]
404 NOTE : Bio::Search::Hit::* classes do not use this code directly; we
405 will deprecate usage of the older tiling code in the next BioPerl
407 - small fixes [cjfields]
409 - Infernal 1.0 output now parsed [cjfields]
410 - new parser for gmap -f9 output [hartzell]
411 - bug 2852 - fix infinite loop in some output [cjfields]
412 - blastxml output now passes all TODO tests [cjfields]
413 - bug 2346, 2850 - psl and exonerate parsing fixes [rbuels, jhannah, bvecchi, YAPC hackathon]
414 - RT 44782 - GbrowseGFF writer now catches evalues [Allen Day]
415 - bug 2575 - add two columns of additional output to HSPTableWriter [cjfields]
416 * Bio::Seq::LargePrimarySeq
417 - delete tempdirs [cjfields]
418 - bug fixes [rbuels, jhannah, bvecchi, YAPC hackathon]
420 - extract regions based on quality threshold value [Dan Bolser, heikki]
421 - bug 2847 - resolve threshold issue (rbuels, jhannah, bvecchi)
422 * Bio::SeqFeature::Lite
423 - various Bio::DB::SeqFeature-related fixes [lstein]
424 * Bio::SeqFeature::Tools::TypeMapper
425 - additional terms for GenBank to SO map [scain]
426 * Bio::SeqIO::chadoxml
427 - bug 2785 - patch to get this working for bp_seqconvert [cjfields]
429 - support for CDS records [dave_messina, Sylvia]
431 - complete refactoring to handle all FASTQ variants, perform validation,
432 write output. API now conforms with other Bio* parsers and the rest of
433 Bio::SeqIO (e.g. write_seq() creates fastq output, not fasta output).
435 * Bio::SeqIO::genbank
436 - bug 2784 - fix DBSOURCE issue [Phillip Garland]
437 - bug RT 44536 - support for UniProt/UniProtKB tests [cjfields]
438 * Bio::SeqIO::largefasta
439 - parser returns a Bio::Seq::LargePrimarySeq [jhannah]
441 - add option for 'single' and 'multiple'
443 - bug 2881 - fix scf round-tripping [Adam Søgren]
445 - bug 2766, 2810 - copy over tags from features, doc fixes [David
448 - bug 2793 - patch for add_seq index issue [jhannah, maj]
449 - bug 2801 - throw if args are required [cjfields]
450 - bug 2805 - uniq_seq returns SimpleAlign and hash ref of sequence types
451 [Tristan Lefebure, maj]
452 - bug fixes from YAPC hackathon [rbuels, jhannah, bvecchi]
453 - fix POD and add get_SeqFeatures filter [maj]
454 * Bio::Tools::dpAlign
455 - add support for LocatableSeq [ymc]
456 - to be moved to a separate distribution [cjfields, rbuels]
457 * Bio::Tools::EUtilities
458 - fix for two bugs from mail list [Adam Whitney, cjfields]
459 - add generic ItemContainerI interface for containing same methods
462 - fix up code, add more warnings [cjfields]
463 - to be moved to a separate distribution [cjfields, rbuels]
464 * Bio::Tools::Primer3
465 - bug 2862 - fenceposting issue fixed [maj]
466 * Bio::Tools::Run::RemoteBlast
467 - tests for remote RPS-BLAST [mcook]
468 * Bio::Tools::SeqPattern
469 - bug 2844 - backtranslate method [rbuels, jhannah, bvecchi]
470 * Bio::Tools::tRNAscanSE
471 - use 'gene' and 'exon' for proper SO, ensure ID is unique [jason]
473 - bug 2456 - fix reroot_tree(), added create_node_on_branch() [maj]
474 * Bio::Tree::Statistics
475 - several methods for calculating Fitch-based score, internal trait
476 values, statratio(), sum of leaf distances [heikki]
478 - bug 2869 - add docs indicating edge case where nodes can be
479 prematurely garbage-collected [cjfields]
480 - add as_text() function to create Tree as a string in specified format
482 * Bio::Tree::TreeFunctionsI
483 - bug 2877 - fix bug where bootstrap assigned to the wrong node [Tristan
485 * Bio::TreeIO::newick
486 - fix small semicolon issue [cjfields]
488 - update to bp_seqfeature_load for SQLite [lstein]
489 - hivq.pl - commmand-line interface to Bio::DB::HIV [maj]
490 - fastam9_to_table - fix for MPI output [jason]
491 - gccalc - total stats [jason]
493 - POD cleanup re: FEEDBACK section [maj, cjfields]
494 - cleanup or fix dead links [cjfields]
495 - Use of no_* methods (indicating 'number of something') is deprecated
496 in favor of num_* [cjfields]
497 - lots of new tests for the above bugs and refactors [everyone!]
498 - new template for Komodo text editor [cjfields]
501 * Feature/Annotation rollback
502 - Problematic changes introduced prior to the 1.5 release have been
503 rolled back. These changes led to subtle bugs involving operator
504 overloading and interface methods.
505 - Behavior is very similar to that for BioPerl 1.4, with tag values
506 being stored generically as simple scalars. Results in a modest
509 - Split into a separate distribution on CPAN, primarily so development
510 isn't reliant on a complete BioPerl release.
511 - Bio::Graphics::Pictogram has been renamed to Bio::Draw::Pictogram but
512 is only available via Subversion (via bioperl-live main trunk)
514 - Common test bed for all BioPerl modules
516 - Common Module::Build-based subclass for all BioPerl modules
517 * Bio::DB::EUtilities
518 - Complete refactoring to split up parsing (Bio::Tools::EUtilities),
519 parameter handling (Bio::Tools::EUtilities::EUtilParameters),
520 and user agent request posting and retrieval
521 * Test implementation and reorganization
522 - Tests have been reorganized into groups based on classes or use
524 - Automated test coverage is now online:
525 http://www.bioperl.org/wiki/Test_Coverage
526 - After this release, untested modules will be moved into a
527 separate developer distribution until tests can be derived.
528 Also, new modules to be added are expected to have a test suite
529 and adequate test coverage.
531 1.5.2 Developer release
533 Full details of changes since 1.5.1 are available online at:
534 http://www.bioperl.org/wiki/Change_log
535 The following represents a brief overview of the most important changes.
538 - Overhaul. Brand new system fully allows markers to have multiple
539 positions on multiple maps, and to have relative positions. Should be
543 - This module and all the modules in the Taxonomy directory now
544 deprecated in favour of Bio::Taxon and Bio::Tree::Tree
549 * get_Taxonomy_Node() eventually to be deprecated, renamed get_taxon().
551 * New methods ancestor(), each_Descendent() and _handle_internal_id().
553 * Allows for different database modules to create Bio::Taxon objects
554 with the same internal id when the same taxon is requested from each.
557 * get_Children_Taxids() is deprecated, superceded by each_Descendent().
559 * No longer includes the fake root node 'root'; there are multiple roots
560 now (10239, 12884, 12908, 29384 and 131567). Consistent with entrez.pm
563 * get_node() has new option -full
565 * Caches data retrieved from website
568 - Now a Bio::Taxon. Carries out the species name -> specific name munging
569 that Bio::DB::Taxonomy modules and SeqIO modules used to do, for
570 backward compatability in species() method.
572 o Bio::Search and Bio::SearchIO
573 - Overhaul. The existing system has been sped up via some minor changes
574 (mostly gain-of-function to the API). Bio::PullParserI is introduced
575 as a potential eventual replacment for the existing system, though as
576 yet only a Hmmpfam parser exists written using it.
579 1.5.1 Developer release
581 o Major problem with how Annotations were written out with
582 Bio::Seq is fixed by reverting to old behavior for
583 Bio::Annotation objects.
588 * bug #1871; REFLOOP' parsing loop, I changed the pattern to
589 expect at l east 9 spaces at the beginning of a line to
590 indicate line wrapping.
592 * Treat multi-line SOURCE sections correctly, this defect broke
593 both common_name() and classification()
595 * parse swissprot fields in genpept file
597 * parse WGS genbank records
600 * Changed regexp for ID line. The capturing parentheses are
601 the same, the difference is an optional repeated-not-semi-
602 colon expression following the captured \S+. This means the
603 regexp works when the division looks like /PRO;/ or when the
604 division looks like /ANG ;/ - the latter is from EMBL
607 * fix ID line parsing: the molecule string can have spaces in
608 it. Like: "genomic DNA"
610 - swiss.pm: bugs #1727, #1734
613 * Added parser for entrezgene ASN1 (text format) files.
614 Uses Bio::ASN1::EntrezGene as a low level parser (get it from CPAN)
618 - maf.pm coordinate problem fixed
620 o Bio::Taxonomy and Bio::DB::Taxonomy
622 - Parse NCBI XML now so that nearly all the taxonomy up-and-down
623 can be done via Web without downloading all the sequence.
625 o Bio::Tools::Run::RemoteBlast supports more options and complies
626 to changes to the NCBI interface. It is reccomended that you
627 retrieve the data in XML instead of plain-text BLAST report to
628 insure proper parsing and retrieval of all information as NCBI
629 fully expects to change things in the future.
631 o Bio::Tree and Bio::TreeIO
633 - Fixes so that re-rooting a tree works properly
635 - Writing out nhx format from a newick/nexus file will properly output
636 bootstrap information. The use must move the internal node labels over
638 for my $node ( grep { ! $_->is_Leaf } $tree->get_nodes ) {
639 $node->bootstrap($node->id);
642 - Nexus parsing is much more flexible now, does not care about
645 - Cladogram drawing module in Bio::Tree::Draw
647 - Node height and depth now properly calculated
649 - fix tree pruning algorithm so that node with 1 child gets merged
651 o Graphics tweaks. Glyph::xyplot improved. Many other small-medium sized
652 bugs and improvements were added, see Gbrowse mailing list for most of
655 o Bio::DB::GFF partially supports GFF3. See information about
656 gff3_munge flag in scripts/Bio-DB-GFF/bulk_load_gff.pl.
658 o Better location parsing in Bio::Factory::FTLocationFactory -
659 this is part of the engine for parsing EMBL/GenBank feature table
660 locations. Nested join/order-by/complement are allowed now
662 o Bio::PrimarySeqI->translate now takes named parameters
664 o Bio::Tools::Phylo::PAML - parsing RST (ancestral sequence
665 reconstruction) is now supported. Parsing different models and
666 branch specific parametes are now supported.
668 o Bio::Factory::FTLocationFactory - parse hierarchical locations
671 o Bio::Matrix::DistanceMatrix returns arrayrefs instead of arrays
672 for getter/setter functions
676 - blast bug #1739; match scientific notation in score
677 and possible e+ values
679 - blast.pm reads more WU-BLAST parameters and parameters, match
680 a full database pathname,
682 - Handle NCBI WEB and newer BLAST formats specifically
683 (Query|Sbjct:) match in alignment blocks can now be (Query|Sbjct).
685 - psl off-by-one error fixed
687 - exonerate parsing much improved, CIGAR and VULGAR can be parsed
688 and HSPs can be constructed from them.
690 - HSPs query/hit now have a seqdesc field filled out (this was
691 always available via $hit->description and
692 $result->query_description
694 - hmmer.pm can parse -A0 hmmpfam files
696 - Writer::GbrowseGFF more customizeable.
698 o Bio::Tools::Hmmpfam
699 make e-value default score displayed in gff, rather than raw score
700 allow parse of multiple records
703 1.5 Developer release
705 o Bio::Align::DNAStatistics and Bio::Align::ProteinStatistics
706 provide Jukes-Cantor and Kimura pairwise distance methods,
709 o Bio::AlignIO support for "po" format of POA, and "maf";
710 Bio::AlignIO::largemultifasta is a new alternative to
711 Bio::AlignIO::fasta for temporary file-based manipulation of
712 particularly large multiple sequence alignments.
714 o Bio::Assembly::Singlet allows orphan, unassembled sequences to
715 be treated similarly as an assembled contig.
717 o Bio::CodonUsage provides new rare_codon() and probable_codons()
718 methods for identifying particular codons that encode a given
721 o Bio::Coordinate::Utils provides new from_align() method to build
722 a Bio::Coordinate pair directly from a
723 Bio::Align::AlignI-conforming object.
725 o Bio::DB::Biblio::eutils is a class for querying NCBI's Eutils.
726 Send a Pubmed, Pubmed Central, Entrez, or other query to NCBI's
727 web service using standard Pubmed query syntax, and retrieve
730 o Bio::DB::GFF has various sundry bug fixes.
732 o Bio::FeatureIO is a new SeqIO-style subsystem for
733 writing/reading genomic features to/from files. I/O classes
734 exist for BED, GTF (aka GFF v2.5), and GFF v3. Bio::FeatureIO
735 classes only read/write Bio::SeqFeature::Annotated objects.
736 Notably, the GFF v3 class requires features to be typed into the
739 o Bio::Graph namespace contains new modules for manipulation and
740 analysis of protein interaction graphs.
742 o Bio::Graphics has many bug fixes and shiny new glyphs.
744 o Bio::Index::Hmmer and Bio::Index::Qual provide multiple-file
745 indexing for HMMER reports and FASTA qual files, respectively.
747 o Bio::Map::Clone, Bio::Map::Contig, and Bio::Map::FPCMarker are
748 new objects that can be placed within a Bio::Map::MapI-compliant
749 genetic/physical map; Bio::Map::Physical provides a new physical
750 map type; Bio::MapIO::fpc provides finger-printed clone mapping
753 o Bio::Matrix::PSM provide new support for postion-specific
754 (scoring) matrices (e.g. profiles, or "possums").
756 o Bio::Ontology::Ontology and Bio::Ontology::Term objects can now
757 be instantiated without explicitly using Bio::OntologyIO. This
758 is possible through changes to Bio::Ontology::OntologyStore to
759 download ontology files from the web as necessary. Locations of
760 ontology files are hard-coded into
761 Bio::Ontology::DocumentRegistry.
763 o Bio::PopGen includes many new methods and data types for
764 population genetics analyses.
766 o New constructor to Bio::Range, unions(). Given a list of
767 ranges, returns another list of "flattened" ranges --
768 overlapping ranges are merged into a single range with the
769 mininum and maximum coordinates of the entire overlapping group.
771 o Bio::Root::IO now supports -url, in addition to -file and -fh.
772 The new -url argument allows one to specify the network address
773 of a file for input. -url currently only works for GET
774 requests, and thus is read-only.
776 o Bio::SearchIO::hmmer now returns individual Hit objects for each
777 domain alignment (thus containing only one HSP); previously
778 separate alignments would be merged into one hit if the domain
779 involved in the alignments was the same, but this only worked
780 when the repeated domain occured without interruption by any
781 other domain, leading to a confusing mixture of Hit and HSP
784 o Bio::Search::Result::ResultI-compliant report objects now
785 implement the "get_statistics" method to access
786 Bio::Search::StatisticsI objects that encapsulate any
787 statistical parameters associated with the search (e.g. Karlin's
788 lambda for BLAST/FASTA).
790 o Bio::Seq::LargeLocatableSeq combines the functionality already
791 found in Bio::Seq::LargeSeq and Bio::LocatableSeq.
793 o Bio::SeqFeature::Annotated is a replacement for
794 Bio::SeqFeature::Generic. It breaks compliance with the
795 Bio::SeqFeatureI interface because the author was sick of
796 dealing with untyped annotation tags. All
797 Bio::SeqFeature::Annotated annotations are Bio::AnnotationI
798 compliant, and accessible through Bio::Annotation::Collection.
800 o Bio::SeqFeature::Primer implements a Tm() method for primer
801 melting point predictions.
803 o Bio::SeqIO now supports AGAVE, BSML (via SAX), CHAOS-XML,
804 InterProScan-XML, TIGR-XML, and NCBI TinySeq formats.
806 o Bio::Taxonomy::Node now implements the methods necessary for
807 Bio::Species interoperability.
809 o Bio::Tools::CodonTable has new reverse_translate_all() and
810 make_iupac_string() methods.
812 o Bio::Tools::dpAlign now provides sequence profile alignments.
814 o Bio::Tools::GFF now parses GFF version 2.5 (a.k.a. GTF).
816 o Bio::Tools::Fgenesh, Bio::Tools::tRNAscanSE are new report
819 o Bio::Tools::SiRNA includes two new rulesets (Saigo and Tuschl)
820 for designing small inhibitory RNA.
822 o Bio::Tree::DistanceFactory provides NJ and UPGMA tree-building
823 methods based on a distance matrix.
825 o Bio::Tree::Statistics provides an assess_bootstrap() method to
826 calculate bootstrap support values on a guide tree topology,
827 based on provided bootstrap tree topologies.
829 o Bio::TreeIO now supports the Pagel (PAG) tree format.
835 o Improvements to Bio::AlignIO::nexus for parsing TreeBase nexus files
837 o Bio::Graphics will work with gd1 or gd2
840 - hmmer.pm Better hmmpfam parsing, fix bug for small number of alignment outputs
842 - blast.pm Parse multi-line query fields properly
843 - small speed improvements to blasttable.pm and others
845 o Bio::DB::Taxonomy has better support for hierarchy traversal so that
846 Bio::Taxonomy::Node can be as simple as Bio::Species object while still
847 supporting more complex queries
850 1.4. Stable major release
852 Since initial 1.2.0, 3000 separate changes have been made to make this release.
854 o installable scripts
856 o global module version from Bio::Root:Version
859 - major improvements; SVG support
862 - population genetics
863 - support several population genetics types of questions.
864 - Tests for statistical neutrality of mutations
865 (Fu and Li's D/F, Tajima's D) are in Bio::PopGen::Statistics.
866 Tests of population structure (Wright's F-statistic: Fst) is in
867 Bio::PopGen::PopStats. Calculating composite linkage
868 disequilibrium (LD) is available in Bio::PopGen::Statistics as
870 - Bio::PopGen::IO for reading in prettybase (SeattleSNPs)
871 and csv (comma delimited formatted) data.
873 - a directory for implementing population simulations has
874 been added Bio::PopGen::Simulation and 2 simulations - a
875 Coalescent and a simple single-locus multi-allele genetic drift
876 simulation have been provided. This replaces the code in
877 Bio::Tree::RandomTree which has been deprecated until proper
878 methods for generating random phylogenetic trees are
882 - new restrion analysis modules
884 o Bio::Tools::Analysis
885 - web based DNA and Protein analysis framework and several
889 - per residue annotable sequences
892 - Bio::Matrix::PSM - Position Scoring Matrix
893 - Bio::Matrix::IO has been added for generalized parsing of
894 matrix data. Matrix::IO::scoring and Matrix::IO::phylip are
895 initial implementations for parsing BLOSUM/PAM and Phylip
896 Distance matricies respectively. A generic matrix
897 implementation for general use was added in
898 Bio::Matrix::Generic.
905 o Bio::Tools::SiRNA, Bio::SeqFeature::SiRNA
906 - small inhibitory RNA
908 o Bio::SeqFeature::Tools
909 - seqFeature mapping tools
910 - Bio::SeqFeature::Tools::Unflattener.pm
911 -- deal with mapping GenBank feature collections into
912 Chado/GFF3 processable feature sets (with SO term mappings)
914 o Bio::Tools::dpAlign
915 - pure perl dynamic programming sequence alignment
918 o new Bio::SearchIO formats
919 - axt and psl: UCSC formats.
920 - blasttable: NCBI -m 8 or -m 9 format from blastall
922 o new Bio::SeqIO formats
923 - chado, tab, kegg, tigr, game
924 - important fixes for old modules
928 o improved Bio::Tools::Genewise
930 o Bio::SeqIO now can recongnize sequence formats automatically from
933 o new parsers in Bio::Tools:
934 Blat, Geneid, Lagan, Mdust, Promoterwise, PrositeScan,
936 o Bio::DB::Registry bugs fixed
937 - BerkeleyDB-indexed flat files can be used by the OBDA system
938 - Multiple seqdatabase.ini locations in OBDA_SEARCH_PATH are all
939 used by the OBDA system
942 - SimpleWebAnalysis, Trees, Feature Annotation, OBDA Access, Flat
945 o hundreds of new and improved files
949 o Bio::Tree::AlleleNode has been updated to be a container of
950 an Bio::PopGen::Individual object for use in the Coalescent simulations.
955 1.2.3 Stable release update
956 o Bug #1475 - Fix and add speedup to spliced_seq for remote location
958 o Bug #1477 - Sel --> Sec abbreviation fixed
959 o Fix bug #1487 where paring in-between locations when
960 end < start caused the FTLocationFactory logic to fail.
961 o Fix bug #1489 which was not dealing with keywords as an
962 arrayref properly (this is fixed on the main trunk because
963 keywords returns a string and the array is accessible via
965 o Bio::Tree::Tree memory leak (bug #1480) fixed
966 Added a new initialization option -nodelete which
967 won't try and cleanup the containing nodes if this
969 o Bug with parsing labeled nodes with Bio::TreeIO::newick fixed
970 this was only present on the branch for the 1.2.1 and 1.2.2 series
971 - Also merged main trunk changes to the branch which make
972 newick -> nhx round tripping more effective (storing branch length
973 and bootstrap values in same locate for NodeNHX and Node
974 implementations.) Fixes to TreeIO parsing for labeled internal
975 also required small changes to TreeIO::nhx. Improved
976 tests for this module as well.
978 - Fixed bugs in BLAST parsing which couldn't parse NCBI
979 gapped blast properly (was losing hit significance values due to
980 the extra unexpeted column).
981 - Parsing of blastcl3 (netblast from NCBI) now can handle case of
982 integer overflow (# of letters in nt seq dbs is > MAX_INT)
983 although doesn't try to correct it - will get the negative
984 number for you. Added a test for this as well.
985 - Fixed HMMER parsing bug which prevented parsing when a hmmpfam report
986 has no top-level family classification scores but does have scores and
987 alignments for individual domains.
988 - Parsing FASTA reports where ungapped percent ID is < 10 and the
989 regular expression to match the line was missing the possibility of
990 an extra space. This is rare, which is why we probably did not
992 - BLAST parsing picks up more of the statistics/parameter fields
993 at the bottom of reports. Still not fully complete.
994 - SearchIO::Writer::HTMLResultWriter and TextResultWriter
995 were fixed to include many improvements and added flexiblity
996 in outputting the files. Bug #1495 was also fixed in the process.
998 - Update for GFF3 compatibility.
999 - Added scripts for importing from UCSC and GenBank.
1000 - Added a 1.2003 version number.
1003 - Added a 1.2003 version number.
1004 o SeqIO::swiss Bug #1504 fixed with swiss writing which was not
1005 properly writing keywords out.
1006 o Bio::SeqIO::genbank
1007 - Fixed bug/enhancement #1513 where dates of
1008 the form D-MMM-YYYY were not parsed. Even though this is
1009 invalid format we can handle it - and also cleanup the date
1010 string so it is properly formatted.
1011 - Bug/enhancement #1517 fixed so that SEGMENT line can be parsed
1012 and written with Genbank format. Similarly bug #1515 is fixed to
1013 parse in the ORIGIN text.
1014 o Bio::SeqIO::fasta, a new method called preferred_id_type allows you
1015 to specify the ID type, one of (accession accession.version
1016 display primary). See Bio::SeqIO::preferred_id_type method
1017 documentation for more information.
1018 o Unigene parsing updated to handle file format changes by NCBI
1020 1.2.2 Stable release update
1022 o A series of bug fixes of the Bio::OntologyIO dagflat-related parsers:
1023 - auto-discover ontology name
1024 - bug in parsing relationships when certain characters are in the term
1025 - fixed hard-coded prefix for term identifiers
1026 - various smaller issues
1028 o Fixed bug in Bio::Annotation::OntologyTerm of not implementing all
1029 of Bio::Ontology::TermI
1031 o brought the OBDA Registry code up to latest specs
1035 - accession number retrieval fixed
1037 o Bio::SearchIO::blast - fix bug #1443 (missing last hits), parse megablast
1039 o Bio::SearchIO::Writer::(HTML|Text)ResultWriter fix bugs #1458,
1040 #1459 which now properly report alignment start/end info
1041 for translated BLAST/FASTA searches.
1043 o Bio::TreeIO::newick can parse labeled internal nodes
1045 o Bio::Tools::BPbl2seq can properly report strand info for HSPs
1046 for BLASTX if if you provide -report_type => 'BLASTX' when
1047 initializing a BPbl2seq object. Bioperl 1.3 will have better
1048 support for bl2seq in the SearchIO system.
1050 o Bio::Root::IO support a -noclose boolean flag which will not
1051 close a filehandle upon object cleanup - useful when sharing
1052 a filehandle among objects. Additionally code added s.t.
1053 STDOUT/STDIN/STDERR will never be closed by Root::IO cleanup.
1055 o Bio::Tools::Genemark bug #1435 fixed which was missing last prediction
1057 o Bio::SeqIO::genbank
1058 - bug #1456 fixed which generated extra sequence lines
1059 - write moltype correctly for genpept
1061 1.2.1 Stable release update
1063 o Inclusion of WrapperBase, a needed component for StandAloneBlast
1065 o Addition from main trunk of Ontology objects, principly to allow
1066 BioSQL releases against 1.2.1
1068 o Fixes and cleanup of Bio::Coordinate modules
1070 o A fix to Bio::Index::EMBL allowing retrieval of entries using
1071 the primary accession number
1073 o Other bug fixes, including bpindex GenBank fix
1075 o Bio::SeqIO::genbank bug #1389 fixed
1077 1.2 Stable major release
1079 o More functionality added to Bio::Perl, the newbie module
1081 o Bug fixes in Bio::TreeIO::newick fixes bug introduced in 1.0.2
1082 Support for New Hampshire Extended (NHX) format parsing.
1084 o Bio::Tools added support for parsing Genomewise, Pseudowise, Est2Genome,
1085 Tmhmm, SignalP, Seg, RepeatMasker, FootPrinter, and a lightweight
1088 o New ontology parsing Bio::Ontology
1090 o Bug fixes in Bio::SearchIO for HMMer parsing, support for
1091 multi-report (mlib) fasta reports, support for waba and exonerate.
1093 o Bio::ClusterIO for parsing Unigene clusters
1095 o Bio::Assembly added for representing phrap and ace assembly clusters.
1097 o Rudimentary support for writing Chado XML (see
1098 GMOD project: www.gmod.org for more information)
1100 o Bio::Coordinate for mapping between different coordinate systems such
1101 as protein -> cDNA -> Exon -> DNA and back. Useful for mapping
1102 features into different coordinate systems.
1104 o Bio::DB::GenBank/Bio::DB::GenPept now support Entrez queries
1105 with the get_Stream_by_query method and supports the latest
1106 NCBI eutils interface.
1108 o Bugs fixed in Bio::SeqFeature::Collection an in-memory fast
1109 object for extracting subsets of features : currently only
1110 supports extraction by location.
1112 1.1.1 Developer release
1114 o Deprecated modules are now listed in the DEPRECATED file
1116 o New HowTo documents located in doc/howto describing
1117 a domain of Bioperl.
1119 o Note that bugs are now stored at redmine.open-bio.org/projects/bioperl/
1120 and all old bugs are searchable through the bugzilla interface.
1122 o Several reported bugs in Bio::Tools::Sigcleave and Bio::SimpleAlign
1123 have been addressed.
1125 o Support for Genewise parsing in Bio::Tools::Genewise
1127 o Start of Ontology framework with Bio::Ontology
1129 o Speedup to the Bio::Root::Root object method _rearrange.
1130 A global _load_module method was implemented to simplify the
1131 dynamic loading of modules ala Bio::SeqIO::genbank. This
1132 method is now used by all the XXIO (AlignIO,TreeIO,SearchIO,SeqIO,
1135 o Several performance improvements to sequence parsing in Bio::SeqIO.
1136 Attempt to speedup by reducing object creation overhead.
1138 o Bio::DB::GenBank and Bio::DB::GenPept use the NCBI's approved
1139 method for sequence retrieval with their E-utils CGI scripts.
1140 More work to support Entrez queries to their fullest is planned
1143 o Numerous fixes to Bio::SearchIO and sequence parsing (swissprot)
1145 1.1 Developer release
1147 o Bio::Tools::Run has been broken off into a new pkg bioperl-run,
1148 this separation removes some of the complexity in our test suite
1149 and separates the core modules in bioperl from those that need
1150 external programs to run.
1152 o With latest ExtUtils::MakeMaker module installed SGI/IRIX should
1153 not run into trouble running the makefile
1155 o Bio::Location and Bio::SeqIO::FTHelper are fixed to properly
1156 read,create,and write locations for grouped/split locations
1157 (like mRNA features on genomic sequence).
1159 o Bio::Tools::Phlyo added for wrappers for parsing Molphy (protml)
1160 and PAML (codeml,aaml, etc) parsing.
1162 o Bio::Tree:: objects expanded to handle testing monophyly,
1163 paraphyly, least common ancestor, etc.
1165 o Bio::Coordinate for mapping locations from different coordinate spaces
1167 o Bio::SearchIO::waba added for parsing WABA, Bio::SearchIO::hmmer
1168 added for parsing hmmpfam and hmmsearch output.
1170 o Bio::SearchIO::Writer::TextResultWriter for outputting
1171 a pseudo-blast textfile format
1174 1.0.2 Bug fix release
1176 o Note: The modules Bio::DB::GenBank and Bio::DB::GenPept provided
1177 in this release will not work after December 2002 when NCBI
1178 shuts off the old Entrez cgi scripts. We have already fixed
1179 on our main development branch and the functionality will be
1180 available in the next stable bioperl release (1.2) slated for
1183 o Numerous parsing bugs in Bio::SearchIO::fasta found through
1184 testset by Robin Emig. These were fixed as was the get_aln
1185 method in Bio::Search::HSP::GenericHSP to handle the extra
1186 context sequence that is provided with a FastA alignment.
1188 o Migrating differences between Bio::Search::XX::BlastXX to
1189 Bio::Search::XX::GenericXX objects. This included mechanism
1190 to retrieve whole list of HSPs from Hits and whole list of Hits from
1191 Results in addition to the current next_XX iterator methods that
1192 are available. Added seq_inds() method to GenericHSP which identifies
1193 indexes in the query or hit sequences where conserved,identical,gaps,
1194 or mismatch residues are located (adapted from Steve Chervitz's
1195 implementation in BlastHSP).
1197 o Bio::DB::GFF bugs fixed and are necessary for latest GBrowse release.
1198 Bio::DB::GFF::RelSegment is now Bio::SeqI compliant.
1200 o Bio::Graphics glyph set improved and extended for GBrowse release
1202 o Bio::Tree::Tree get_nodes implementation improvement thanks
1203 to Howard Ross notice performance problem when writing out
1206 o Bio::Location::Fuzzy::new named parameter -loc_type became
1207 -location_type, Bio::Location::Simple::new named parameter
1208 -seqid becamse -seq_id.
1210 o Fixed major Bio::AlignIO::emboss parsing bug on needle output,
1211 was mis-detecting that gaps should be placed at the beginning of
1212 the alignment when the best alignment starts internally in the
1215 1.0.1 Bug fix release
1217 o Minor bug fixes to Bio::DB:GFF. Glyph sets improved.
1219 o Parser fixes in SearchIO blast, fasta for more complete WU BLAST
1220 and mixed (3.3 - 3.4) versions of FASTA.
1222 o Small API change to add methods for completeness across
1223 implementations of Bio::Search objects. These new methods
1224 in the interface are implemented by the GenericXX object as well
1225 as the BlastXX objects.
1226 * Bio::Search::Result::ResultI
1227 - hits() method returns list of all Hits (next_hit is an
1230 * Bio::Search::Hit::HitI
1231 - hsps() method returns list of all HSPs (next_hsp is an
1234 o The Bio::SearchIO::Writer classes have been fixed to handle results
1235 created from either psiblast (Search::BlastXX objects) or
1236 blast|fasta|blastxml objects (Search::GenericXX objects). More work
1237 has to be done here to make it work properly and will nee major
1240 o Bugs in Bio::Tools::HMMER fixed, including
1241 * #1178 - Root::IO destructor wasn't being called
1242 * #1034 - filter_on_cutoff now behaves properly
1244 o Bio::SeqFeature::Computation initialization args fixed and
1247 o Tests are somewhat cleaner, flat.t now properly cleans up after itsself,
1249 o Updated FAQ with more example based answers to typical questions
1251 o Bug #1202 was fixed which would improperly join together qual values
1252 parsed by Bio::SeqIO::qual when a trailing space was not present before
1255 1.0.0 Major Stable Release
1257 This represents a major release of bioperl with significant
1258 improvements over the 0.7.x series of releases.
1260 o Bio::Tools::Blast is officially deprecated. Please see
1261 Bio::SearchIO for BLAST and FastA parsing.
1263 o The methods trunc() and subseq() in Bio::PrimarySeqI now accepts
1264 Bio::LocationI objects as well as start/end.
1266 o Bio::Biblio contains modules for Bibliographic data.
1267 Bio::DB::Biblio contains the query modules. Additionally one can
1268 parse medlinexml from the ebi bibliographic query service (BQS)
1269 system and Pubmed xml from NCBI. See Martin Senger's
1270 documentation in Bio::Biblio for more information.
1272 o Bio::DB::Registry is a sequence database registry part of
1273 Open Bioinformatics Database Access. See
1274 http://obda.open-bio.org for more information.
1276 o File-based and In-Memory Sequence caching is provided by
1277 Bio::DB::InMemoryCache and Bio::DB::FileCache which acts like a
1280 o Bio::Graphics for rendering sequences as PNG,JPG, or GIFs has
1281 been added by Lincoln Stein.
1283 o XEMBL SOAP service access in provided in Bio::DB::XEMBL.
1285 o A FAQ has been started and is included in the release to provide
1286 a starting point for frequent questions and issues.
1288 0.9.3 Developer's release
1290 o Event based parsing system improved (SearchIO). With parsers for
1291 XML Blast (blastxml), Text Blast (blast), and FASTA results (fasta).
1292 Additionally a lazy parsing system for text and html blast reports was
1293 added and is called psiblast (name subject to change in future releases).
1295 o Bio::Search objects improved and standardized with associated Interfaces
1296 written. The concept of a search "Hit" was standardized to be called
1297 "hit" consistently and the use of "subject" was deprecated in all active
1300 o Bio::Structure added (since 0.9.1) for Protein structure objects
1301 and PDB parser to retrieve and write these structures from data files.
1303 o Several important Bio::DB::GFF bug fixes for handling features that
1304 are mapped to multiple reference points. Updated mysql adaptor
1305 so as to be able to store large (>100 megabase) chunks of DNA into
1306 Bio::DB::GFF databases.
1308 0.9.2 Developer's release
1310 o Bio::Search and Bio::SearchIO system introduced for event based
1311 parsing of Blast,Fasta reports Bio::SearchIO supports ncbi BLAST
1312 in text and XML and FASTA reports in standard output format.
1314 o Bio::Tree and Bio::TreeIO for phylogenetic trees. A Random tree
1315 generator is included in Bio::TreeIO::RandomTrees and a
1316 statistics module for evaluating.
1318 o Bio::DB::GFF, Lincoln Stein's GFF database suitable as a DB
1319 server for DAS servers.
1321 o Bio::Tools::BPlite is provides more robust parsing of BLAST
1322 files. The entire BPlite system migrated to using Bio::Root::IO
1323 for the data stream.
1325 o Bio::Tools::Alignment for Consed and sequence Trimming
1328 o Bio::Structure for Protein structure information and parsing
1330 o Bio::DB::GenBank/Bio::DB::GenPept updated to new NCBI Entrez
1331 cgi-bin entry point which should be more reliable.
1333 o Bio::Map and Bio::MapIO for biological map navigation and a
1334 framework afor parsing them in. Only preliminary work here.
1336 o Interface for executing EMBOSS programs locally in Bio::Factory::EMBOSS
1337 Future work will integrate Pise and allow submission of analysis on
1340 o Bio::AnnotationCollectionI and Bio::Annotation::Collection
1341 introduced as new objects for handling Sequence Annotation
1342 information (dblinks, references, etc) and is more robust that
1345 o Bio::Tools::FASTAParser introduced.
1347 o Scripts from the bioperl script submission project and new
1348 scripts from bioperl authors are included in "scripts" directory.
1350 o Factory objects and interfaces are being introduced and are more
1353 o Bio::Root::Root introduced as the base object while
1354 Bio::Root::RootI is now simply an interface.
1356 o Bio::DB::RefSeq provides database access to copy of the NCBI
1357 RefSeq database using the EBI dbfetch script.
1359 0.9.0 Developer's release
1361 o perl version at least 5.005 is now required instead of perl 5.004
1363 o Bio::Tools::Run::RemoteBlast is available for running remote
1366 o Bio::Tools::BPbl2seq was fixed to handle multiple HSPs.
1368 o Bio::SeqFeature::GeneStructure migrated to Bio::SeqFeature::Gene.
1369 Also added are related modules UTR3, UTR5, Exon, Intron,
1370 Promotor, PolyA and Transcript.
1372 o Speedup of translate method in PrimarySeq
1374 o Bio::SimpleAlign has new methods: location_from_column(), slice(),
1375 select(), dot(), get_seq_by_pos(), column_from_residue_number()
1377 o Various fixes to Variation toolkit
1379 o Bio::DB::EMBL provides database access to EMBL sequence data.
1380 Bio::DB::Universal provides a central way to point to indexes
1381 and dbs in a single interface.
1383 o Bio::DB::GFF - a database suitable for running DAS servers locally.
1385 o Bio::Factory::EMBOSS is still in design phase as is
1386 Bio::Factory::ApplicationFactoryI
1388 o Dia models for bioperl design are provided in the models/ directory
1390 0.7.2 Bug fix release
1392 o documentation fixes in many modules - SYNOPSIS code verified
1393 to be runnable in many (but not all modules)
1395 o corrected MANIFEST file from 0.7.1 release
1397 o Bug fix in Bio::SeqIO::FTHelper to properly handle
1400 o Bio::SeqIO::genbank
1401 * Correct parsing and writing of genbank format with protein data
1402 * moltype and molecule separation
1404 o Bio::SeqIO::largefasta fix to avoid inifinite loops
1406 o Bio::SimpleAlign fixed to correctly handle consensus
1407 sequence calculation
1409 o Bio::Tools::HMMER supports hmmer 2.2g
1411 o Bio::Tools::BPlite to support report type specific parsing. Most
1412 major changes are not on the 0.7 branch.
1414 o Bio::Tools::Run::StandAloneBlast exists_blast() fixed and works
1417 o Bio::Variation::AAChange/RNAChange corrected labels and mutated alleles
1418 in several types of mutations:
1419 1.) AA level: deletion, complex
1420 2.) AA level: complex, inframe
1421 3.) RNA level: silent
1423 o BPbl2seq parsing of empty reports will not die, but will return
1424 a valid, empty, Bio::SeqFeature::SimilarityFeature for
1425 $report->query() and $report->subject() methods. So an easy
1426 way to test if report was empty is to see if
1427 $report->query->seqname is undefined.
1429 0.7.1 Bug fix release
1431 o Better parsing of genbank/EMBL files especially fixing bugs
1432 related to Feature table parsing and locations on remote
1433 sequences. Additionally, species name parsing was better.
1435 o Bio::SeqIO::genbank can parse now NCBI produced genbank database
1436 which include a number of header lines.
1438 o More strict genbank and EMBL format writing (corrected number of
1439 spaces where appropriate).
1441 o Bio::Tools::BPlite can better parse BLASTX reports - see BUGS
1442 for related BPlite BUGS that are unresolved in this release.
1444 o Bio::DB::GenBank, Bio::DB::GenPept have less problems
1445 downloading sequences from NCBI via HTTP. Bio::DB::SwissProt can
1446 use expasy mirrors or EBI dbfetch cgi-script.
1448 o A moderate number of documentation improvements were made as
1449 well to provide a better code synopsis in each module.
1452 0.7 Large number of changes, including refactoring of the
1453 Object system, new parsers, new functionality and
1454 all round better system. Highlights are:
1457 o Refactored root of inheritance: moved to a lightweight Bio::Root::RootI;
1458 Bio::Root::IO for I/O and file/handle capabilities.
1460 o Imported BPlite modules from Ian Korf for BLAST
1461 parsing. This is considered the supported BLAST parser;
1462 Bio::Tools::Blast.pm will eventually phase out due to lack of support.
1464 o Improved Sequence Feature model. Added complete location
1465 modelling (with fuzzy and compound locations). See
1466 Bio::LocationI and the modules under Bio/Location. Added
1467 support in Genbank/EMBL format parsing to completely parse
1468 feature tables for complex locations.
1470 o Moved special support for databanks etc to specialized modules under
1471 Bio/Seq/. One of these supports very large sequences through
1472 a temporary file as a backend.
1474 o Explicit Gene, Transcript and Exon SeqFeature objects, supporting
1475 CDS retrieval and exon shuffling.
1477 o More parsers: Sim4, Genscan, MZEF, ESTScan, BPbl2seq, GFF
1479 o Refactored Bio/DB/GenBank+GenPept. There is now also DB/SwissProt and
1480 DB/GDB (the latter has platform-specific limitations).
1482 o New analysis parser framework for HT sequence annotation (see
1483 Bio::SeqAnalysisParserI and Bio::Factory::SeqAnalysisParserFactory)
1485 o New Alignment IO framework
1487 o New Index modules (Swissprot)
1489 o New modules for running Blast within perl
1490 (Bio::Tools::Run::StandAloneBlast). Added modules for running
1491 Multiple Sequence Alignment tools ClustalW and TCoffee
1492 (Bio::Tools::Run::Alignment).
1494 o New Cookbook-style tutorial (see bptutorial.pl). Improved
1495 documentation across the package.
1497 o Much improved cross platform support. Many known incompatibilities
1498 have been fixed; however, NT and Mac do not work across the entire
1499 setup (see PLATFORMS).
1501 o Many bug fixes, code restructuring, etc. Overall stability and
1502 maintainability benefit a lot.
1504 o A total of 957 automatic tests
1509 There are very few functionality changes but a large
1510 number of software improvements/bug fixes across the package.
1512 o The EMBL/GenBank parsing are improved.
1514 o The Swissprot reading is improved. Swissprot writing
1515 is disabled as it doesn't work at all. This needs to
1516 wait for 0.7 release
1518 o BLAST reports with no hits are correctly parsed.
1520 o Several other bugs of the BLAST parser (regular expressions, ...)
1523 o Old syntax calls have been replaced with more modern syntax
1525 o Modules that did not work at all, in particular the Sim4
1526 set have been removed
1528 o Bio::SeqFeature::Generic and Bio::SeqFeature::FeaturePair
1529 have improved compliance with interface specs and documentation
1531 o Mailing list documentation updated throughout the distribution
1533 o Most minor bug fixes have happened.
1535 o The scripts in /examples now work and have the modern syntax
1536 rather than the deprecated syntax
1539 0.6.1 Sun April 2 2000
1541 o Sequences can have Sequence Features attached to them
1542 - The sequence features can be read from or written to
1543 EMBL and GenBank style flat files
1545 o Objects for Annotation, including References (but not
1546 full medline abstracts), Database links and Comments are
1549 o A Species object to represent nodes on a taxonomy tree
1552 o The ability to parse HMMER and Sim4 output has been added
1554 o The Blast parsing has been improved, with better PSI-BLAST
1555 support and better overall behaviour.
1557 o Flat file indexed databases provide both random access
1558 and sequential access to their component sequences.
1560 o A CodonTable object has been written with all known
1561 CodonTables accessible.
1563 o A number of new lightweight analysis tools have been
1564 added, such as molecular weight determination.
1566 The 0.6 release also has improved software engineering
1568 o The sequence objects have been rewritten, providing more
1569 maintainable and easier to implement objects. These
1570 objects are backwardly compatible with the 0.05.1 objects
1572 o Many objects are defined in terms of interfaces and then
1573 a Perl implementation has been provided. The interfaces
1574 are found in the 'I' files (module names ending in 'I').
1576 This means that it is possible to wrap C/CORBA/SQL access
1577 as true "bioperl" objects, compatible with the rest of
1580 o The SeqIO system has been overhauled to provide better
1581 processing and perl-like automatic interpretation of <>
1584 o Many more tests have been added (a total of 172 automatic
1585 tests are now run before release).
1589 0.05.1 Tue Jun 29 05:30:44 1999
1590 - Central distribution now requires Perl 5.004. This was
1591 done to get around 5.003-based problems in Bio/Index/*
1593 - Various bug fixes in the Bio::Tools::Blast modules
1594 including better exception handling and PSI-Blast
1595 support. See Bio/Tools/Blast/CHANGES for more.
1596 - Fixed the Parse mechanism in Seq.pm to use readseq.
1597 Follow the instructions in README for how to install
1598 it (basically, you have to edit Parse.pm).
1599 - Improved documentation of Seq.pm, indicating where
1600 objects are returned and where strings are returned.
1601 - Fixed uninitialized warnings in Bio::Root::Object.pm
1602 and Bio::Tools::SeqPattern.pm.
1603 - Bug fixes for PR#s: 30,31,33-35,41,42,44,45,47-50,52.
1605 0.05 Sun Apr 25 01:14:11 1999
1606 - Bio::Tools::Blast modules have less memory problems
1607 and faster parsing. Webblast uses LWP and supports
1608 more functionality. See Bio/Tools/Blast/CHANGES for more.
1609 - The Bio::SeqIO system has been started, moving the
1610 sequence reformatting code out of the sequence object
1611 - The Bio::Index:: system has been started, providing
1612 generic index capabilities and specifically works for
1613 Fasta formatted databases and EMBL .dat formatted
1615 - The Bio::DB:: system started, providing access to
1616 databases, both via flat file + index (see above) and
1618 - The scripts/ directory, where industrial strength scripts
1619 are put has been started.
1620 - Many changes - a better distribution all round.
1622 0.04.4 Wed Feb 17 02:20:13 1999
1623 - Bug fixes in the Bio::Tools::Blast modules and postclient.pl
1624 (see Bio::Tools::Blast::CHANGES).
1625 - Fixed a bug in Bio::Tools::Fasta::num_seqs().
1626 - Beefed up the t/Fasta.t test script.
1627 - Small fix in Bio::Seq::type() (now always returns a string).
1628 - Changed Bio::Root::Utilities::get_newline_char() to
1629 get_newline() since it could return more than one char.
1630 - Added $NEWLINE and $TIMEOUT_SECS to Bio::Root::Global.
1631 - Changed default timeout to 20 seconds (was 3).
1632 - Moved lengthy modification notes to the bottom of some files.
1633 - Fixed SimpleAlign write_fasta bug.
1634 - Beefed up SimpleAlign.t test
1636 0.04.3 Thu Feb 4 07:48:53 1999
1637 - Bio::Root::Object.pm and Global.pm now detect when
1638 script is run as a CGI and suppress output that is only
1639 appropriate when running interactively.
1640 - Bio::Root::Err::_set_context() adds name of script ($0).
1641 - Added comments in Bio::Tools::WWW.pm and Bio::Root::Utilities.pm
1642 regarding the use of the static objects via the qw(:obj) tag.
1643 - Fixed the ambiguous reverse calls in Seq.pm and UnivAln.pm to
1644 CORE::reverse, avoiding Perl warnings.
1645 - Bug fixes in Bio::Tools::Blast modules (version 0.074) and
1646 example scripts (see Bio::Tools::Blast::CHANGES).
1647 - examples/seq/seqtools.pl no longer always warns about using
1648 -prot or -nucl command-line arguments; only when using the
1650 - Methods added to Bio::Root::Utilities: create_filehandle(),
1651 get_newline_char(), and taste_file() to generalize filehandle
1652 creation and autodetect newline characters in files/streams
1653 (see bug report #19).
1654 - Bio::Root::IOManager::read() now handles timeouts and uses
1655 Utilities::create_filehandle().
1656 - Bio::Tools::Fasta.pm uses Utilities::get_newline_char() instead
1657 of hardwiring in "\n".
1658 - Bug fixes in the Bio::SimpleAlign and Bio::Tools::pSW
1660 0.04.2 Wed Dec 30 02:27:36 1998
1661 - Bug fixes in Bio::Tools::Blast modules, version 0.073
1662 (see Bio::Tools::Blast::CHANGES).
1663 - Changed reverse calls in Bio/Seq.pm and Bio/UnivAln.pm
1664 to CORE::reverse (prevents ambiguous warnings with 5.005).
1665 - Appending '.tmp.bioperl' to temporary files created by
1666 Bio::Root::Utilities::compress() or uncompress() to
1667 make it easy to identify & cleanup these files as needed.
1668 - Developers: Created CVS branch release-0-04-bug from
1669 release-0-04-1. Before making bug fixes to the 0.04.1 release,
1670 be sure to cvs checkout this branch into a clean area.
1672 0.04.1 Wed Dec 16 05:39:15 1998
1673 - Bug fixes in Bio::Tools::Blast modules, version 0.072
1674 (see Bio::Tools::Blast::CHANGES).
1675 - Compile/SW/Makefile.PL now removes *.o and *.a files
1678 0.04 Tue Dec 8 07:49:19 1998
1679 - Lots of new modules added including:
1680 * Ewan Birney's Bio::SimpleAlign.pm, Bio::Tools::AlignFactory.pm,
1681 and Bio/Compile directory containing XS-linked C code for
1682 creating Smith-Waterman sequence alignments from within Perl.
1683 * Steve Chervitz's Blast distribution has been incorporated.
1684 * Georg Fuellen's Bio::UnivAln.pm for multiple alignment objects.
1685 - Bio/examples directory for demo scripts for all included modules.
1686 - Bio/t directory containing test suit for all included modules.
1687 - For changes specific to the Blast-related modules prior to
1688 incorporation in this central distribution, see the CHANGES
1689 file in the Bio/Tools/Blast directory.
1691 0.01 Tue Sep 8 14:23:22 1998
1692 - original version from central CVS tree; created by h2xs 1.18